• 介绍：

  Paclitaxel 是一种天然抗肿瘤药，可稳定微管蛋白 (tubulin) 的聚合。Paclitaxel 可导致有丝分裂停滞和诱导细胞凋亡 (apoptosis)，最终导致细胞死亡。Paclitaxel 还可诱导细胞自噬 (autophagy)。

• 熔点： 213-216°C

• 沸点： 957.115 °C at 760 mmHg

• 比旋光度： -49.0°-55.0°(甲醇)

• 外观： 白色结晶体粉末

• 溶解性： DMSO  :  100  mg/mL  (117.11  mM;  Need  ultrasonic)
  
  H2O  :  <  0.1  mg/mL  (insoluble)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

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• 59. [IF=1.779] Xin Hua et al."Combination of oridonin and TRAIL induces apoptosis in uveal melanoma cells by upregulating DR5."Int J Ophthalmol-Chi. 2021; 14(12): 1834–1842

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• 9. 王永红, 于洪丽, 秦梦,等. 紫杉醇/油酰壳聚糖纳米粒的理化特性及肺急性毒性评价[J]. 中国药学杂志, 2018, 053(017):1485-1491.

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• 6. 蒋爱, 李国源, 王鑫,等. 星点设计-效应面法优化紫杉醇-白桦脂酸混合纳米混悬剂[J]. 中草药, 2019, 50(04):852-859.

• 5. 褚冰, 丁敏, 易琼. 抗EGFR单克隆抗体偶联载紫杉醇纳米粒对胃癌肿瘤靶向性能力研究[J]. 贵州医药, 2016(6期):563-566.

• 4. 尹杨峰 蒋磊.千金藤素通过MAT2B调节MAPK信号通路对宫颈癌细胞增殖和凋亡的影响[J].中国医药生物技术 2020 15(02):183-189.

• 3. 王光杰 顾俊峰 肖昀. 代谢型谷氨酸受体5在周围神经痛大鼠脊髓和背根神经节的表达[J]. 中华实用诊断与治疗杂志 2019(11).

• 2. 马生军 刘建慧 马留纯 王颖 曹雪琴 罗建民.不同产地及生长年限曼地亚红豆杉中10-脱乙酰基巴卡亭Ⅲ、三尖杉宁碱、紫杉醇量的比较分析[J].中草药 2017 48(23):4979-4985.

• 1. 李昆太 彭卫福 周佳 等. 一株产紫杉醇的南方红豆杉内生菌的分离与鉴定[J]. 江西农业大学学报 2013 035(001):184-188.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *