• 提示：详情请下载说明书。

• Molecular weight：160 kDa。

• Unit definition：One unit will convert one micromole of Xanthine to Uric acid per min at pH 7.5 at 37℃.

• Isoelectric point： 4.0。

• Michaelis constant: 1.4×10 M (Xanthine)。

• Optimum pH: 7.0~ 7.5。

• Optimum temperature: 55℃。

• pH Stability ：6.0~9.5(30℃,16hr)。

• Thermal stability： < 55℃ (pH 7.5, 20min)。

• Inhibitors： Ag ,Hg。

• 微红色至褐色无定形粉末。能溶于水。微生物提取。主要抑制剂有Ag+，Hg2+，Cd2+及尿素、氰化物、磷酸根和氯离子,主要稳定剂有水杨酸盐、半胱氨酸、组胺和维尔烯酸盐。

• 它是一种催化黄嘌呤、次黄嘌呤生成尿酸的酶，它常作工具酶。用于黄嘌呤、次黄嘌呤、肌苷、鸟嘌呤、鸟苷等的测定

• 储存条件： -20℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 78. [IF=3.3] Jia-Xin Lin et al."Fermentation of olive pulp by Limosilactobacillus fermentum NCU001464: physicochemical properties, biological activity and bioactive phenols."INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY.2024 Jan;:

• 77. [IF=4.6] Xinhe Wang et al."Analysis of Polyphenol Extract from Hazel Leaf and Ameliorative Efficacy and Mechanism against Hyperuricemia Zebrafish Model via Network Pharmacology and Molecular Docking."MOLECULES.2024 Jan;29(2):317

• 76. [IF=5.6] Can Liang et al."Potential antioxidative and anti-hyperuricemic components in Rodgersia podophylla A. Gray revealed by bio-affinity ultrafiltration with SOD and XOD."Frontiers in Pharmacology.2023; 14: 1298049

• 75. [IF=5.9] Qian-Qian Li et al."Hollow Mesoporous Prussian Blue Nanoparticles Loaded with Daunorubicin for Acute Myeloid Leukemia Treatment."ACS Applied Nano Materials.2023;XXXX(XXX):XXX-XXX

• 74. [IF=5.2] Zhipeng Zheng et al."Polyphenol Composition, Antioxidant Capacity and Xanthine Oxidase Inhibition Mechanism of Furong Plum Fruits at Different Maturity Stages."Foods.2023 Jan;12(23):4253

• 73. [IF=6.1] Guojian Wu et al."Dual-Modal Bimetallic Nanozyme-Based Sensing Platform Combining Colorimetric and Photothermal Signal Cascade Catalytic Enhancement for Detection of Hypoxanthine to Judge Meat Freshness."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;71(4

• 72. [IF=8] Jiangjuan Yuan et al."Efficient, stable and sustainable Alginate@Chitosan enzymatic microreactors based on gas-shearing microfluidics."COMPOSITES COMMUNICATIONS.2023 Dec;44:101765

• 71. [IF=8.9] Yanhui Bi et al."Slippery Viscosity-Sensing Platform with Time Readout for the Detection of Hyaluronidase and Its Inhibitor."ACS Sensors.2023;XXXX(XXX):XXX-XXX

• 70. [IF=4.2] Yan Wu et al."Ratiometric SERS Sensor with One Signal Probe for Ultrasensitive and Quantitative Monitoring of Serum Xanthine."ANALYST.10.1039/D3AN01245J

• 69. [IF=5.2] Weimin Hu et al."Identification of anti-hyperuricemic components from Cichorium intybus L. taproots."Food Bioscience.10.1016/j.fbio.2023.103145

• 68. [IF=5.2] Hai-Li Zhou et al."Fermentation of Rosa roxburghii Tratt by Limosilactobacillus fermentum NCU001464: Physicochemical characteristics and biological activity."Food Bioscience.2023 Aug;:103038

• 67. [IF=8.2] Ye Lou et al."Ferulic acid ameliorates hyperuricemia by regulating xanthine oxidase."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Aug;:126542

• 66. [IF=4.3] Lu Manman et al."Cu-MOF derived CuO@g-C3N4 nanozyme for cascade catalytic colorimetric sensing."ANALYTICAL AND BIOANALYTICAL CHEMISTRY.2023 Jul;:1-12

• 65. [IF=6.1] Hongyuan Wu et al."Two dimensional iron metal-organic framework nanosheet with peroxidase-mimicking activity for colorimetric detection of hypoxanthine related to shrimp freshness."TALANTA.2023 Dec;265:124833

• 64. [IF=12.545] Hongen Chang et al."Flexible needle-type Microbiosensor for real-time monitoring traditional acupuncture-mediated adenosine release In vivo."BIOSENSORS & BIOELECTRONICS.2023 Sep;235:115383

• 63. [IF=4.682] Wang Yijie et al."A portable and quantitative detection of xanthine and xanthine oxidase based on cascade enzymatic reactions of Fe3O4@MWCNTs/Hemin."JOURNAL OF MATERIALS SCIENCE.2023 Apr;:1-15

• 62. [IF=10.05] Yuanhua Zhang et al."Surface Patterning Enhanced Visualization for Ultrasensitive Naked-Eye Detection and RGB-Based High-Density Information Storage."Advanced Optical Materials.2023 Apr;:2300010

• 61. [5.318] Qingqing Hu et al."Isolation and characterization of uric acid-lowering functional components from Polygonum cuspidatum."Food Bioscience.2023 Jun;53:102314

• 60. [5.307] Zean Zhao et al."Pharmacological evaluation of a novel skeleton compound isobavachin (4′,7-dihydroxy-8-prenylflavanone) as a hypouricemic agent: Dual actions of URAT1/GLUT9 and xanthine oxidase inhibitory activity."BIOORGANIC CHEMISTRY.2023 Apr;133:106405

• 59. [5.318] Yingling Sui et al."Identification of anti-hyperuricemic components from Coix seed."Food Bioscience.2023 Apr;52:102461

• 58. [5.743] Tao Tian et al."A Catechol-Meter Based on Conventional Personal Glucose Meter for Portable Detection of Tyrosinase and Sodium Benzoate."Biosensors-Basel.2022 Dec;12(12):1084

• 57. [IF=6.911] Qinqin Yang et al."Cu nanoclusters decorated Ti3C2 nanosheets composite with tetraenzyme mimic activities and the application for smartphone-assisted detection of hypoxanthine."ANALYTICA CHIMICA ACTA.2022 Oct;:340494

• 56. [IF=9.231] Qiang Zhao et al."Exploration, sequence optimization and mechanism analysis of novel xanthine oxidase inhibitory peptide from Ostrea rivularis Gould."FOOD CHEMISTRY.2023 Mar;404:134537

• 55. [IF=6.056] Qiang Zhao et al."Separation, identification and docking analysis of xanthine oxidase inhibitory peptides from pacific cod bone-flesh mixture."LWT-FOOD SCIENCE AND TECHNOLOGY.2022 Sep;167:113862

• 54. [IF=7.675] Jing Li et al."Potential Antioxidative and Anti-Hyperuricemic Components Targeting Superoxide Dismutase and Xanthine Oxidase Explored from Polygonatum Sibiricum Red.."Antioxidants.2022 Sep;11(9):1651

• 53. [IF=7.392] Qijun Sun et al."Rice straw-derived carbon based nanozyme sensor: Application of identifying human urine xanthine content and study of active sites."APPLIED SURFACE SCIENCE.2022 Nov;602:154372

• 52. [IF=4.24] Jun Li et al."In vitro xanthine oxidase inhibitory properties of Flos Sophorae Immaturus and potential mechanisms."Food Biosci. 2022 Jun;47:101711

• 51. [IF=13.273] Liying Zhang et al."2D MoSe2@PVP nanosheets with multi-enzyme activity alleviate the acute pancreatitis via scavenging the reactive oxygen and nitrogen species."CHEMICAL ENGINEERING JOURNAL. 2022 Oct;446:136792

• 50. [IF=6.843] Shuhan Jia et al."Dopamine-derived nanoparticles for the protection of irradiation-induced intestinal injury by maintaining intestinal homeostasis."Biomaterials Science. 2022 May;:

• 49. [IF=6.576] Rui Wang et al."Quality Characteristics and Inhibitory Xanthine Oxidase Potential of 21 Sour Cherry (Prunus Cerasus L.) Varieties Cultivated in China."Front Nutr. 2021; 8: 796294

• 48. [IF=4.35] Tingting Han et al."A Water-Dispersible Carboxylated Carbon Nitride Nanoparticles-Based Electrochemical Platform for Direct Reporting of Hydroxyl Radical in Meat."Foods. 2022 Jan;11(1):40

• 47. [IF=7.711] Mei Zhao et al."Viscosity-Based Flow Sensor on Paper for Quantitative and Label-Free Detection of α-Amylase and Its Inhibitor."Acs Sensors. 2022;XXXX(XXX):XXX-XXX

• 46. [IF=2.647] Wang Yujun et al."Zn–porphyrin metal–organic framework–based photoelectrochemical enzymatic biosensor for hypoxanthine."J Solid State Electr. 2022 Feb;26(2):565-572

• 45. [IF=9.594] Shan Chen et al."Plasmonic imaging the catalysis of single graphene sheets – The edge effect."Carbon. 2022 May;191:333

• 44. [IF=4.616] Yiyin Zhang et al."Fe-Doped polydopamine nanoparticles with peroxidase-mimicking activity for the detection of hypoxanthine related to meat freshness."Analyst. 2022 Feb;:

• 43. [IF=10.435] Xie Pei et al."Biodegradable MoSe2-polyvinylpyrrolidone nanoparticles with multi-enzyme activity for ameliorating acute pancreatitis."J Nanobiotechnol. 2022 Dec;20(1):1-18

• 42. [IF=6.312] Min-Xia Fan et al."Potential Antioxidative Components in Azadirachta indica Revealed by Bio-Affinity Ultrafiltration with SOD and XOD."Antioxidants-Basel. 2022 Apr;11(4):658

• 41. [IF=10.588] Huiwang Dai et al.Unveiling the role of cobalt species in the Co/N-C catalysts-induced peroxymonosulfate activation process.J Hazard Mater. 2021 Nov;:127784

• 40. [IF=1.554] Lang Zhang et al."Screening and analysis of xanthine oxidase inhibitors in jute leaves and their protective effects against hydrogen peroxide-induced oxidative stress in cells."Open Chem. 2020 Jan;18(1):1481-1494

• 39. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788

• 38. [IF=3.535] Zhao-Yu Wu et al."Evaluation of xanthine oxidase inhibitory activity of flavonoids by an online capillary electrophoresis-based immobilized enzyme microreactor."Electrophoresis. 2020 Aug;41(15):1326-1332

• 37. [IF=3.591] Xin Wang et al."Colorimetric detection of hypoxanthine in aquatic products based on the enzyme mimic of cobalt-doped carbon nitride."New J Chem. 2021 Oct;45(39):18307-18314

• 36. [IF=4.219] Huilong Xiang et al."Network pharmacology and molecular docking analysis on molecular targets: Mechanisms of baicalin and baicalein against hyperuricemic nephropathy."Toxicol Appl Pharm. 2021 Aug;424:115594

• 35. [IF=4.411] Cong-Peng Zhao et al."Evaluation of Enzyme Inhibitory Activity of Flavonoids by Polydopamine-Modified Hollow Fiber-Immobilized Xanthine Oxidase."Molecules. 2021 Jan;26(13):3931

• 34. [IF=4.411] Xiaosheng Tang et al."Screening and Evaluation of Xanthine Oxidase Inhibitors from Gnetum parvifolium in China."Molecules. 2019 Jan;24(14):2671

• 33. [IF=5.833] Liang Haixia et al."Carbon quantum Dot@Silver nanocomposite–based fluorescent imaging of intracellular superoxide anion."Microchim Acta. 2020 Sep;187(9):1-9

• 32. [IF=6.312] Xiao-Cui Zhuang et al."New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS with SOD and XOD Enzymes."Antioxidants-Basel. 2021 Mar;10(3):370

• 31. [IF=6.986] Qiaoyun Lu et al."Dual-Emission Reverse Change Ratio Photoluminescence Sensor Based on a Probe of Nitrogen-Doped Ti3C2 Quantum Dots@DAP to Detect H2O2 and Xanthine."Anal Chem. 2020;92(11):7770–7777

• 30. [IF=9.518] Lian-Hua Xu et al."ATMP-induced three-dimensional conductive polymer hydrogel scaffold for a novel enhanced solid-state electrochemiluminescence biosensor."Biosens Bioelectron. 2019 Oct;143:111601

• 29. [IF=10.618] Jiantao Ping et al."Hydrogel-assisted paper-based lateral flow sensor for the detection of trypsin in human serum."Biosens Bioelectron. 2021 Nov;192:113548

• 28. [IF=13.273] Peili Li et al."Low-drug resistance carbon quantum dots decorated injectable self-healing hydrogel with potent antibiofilm property and cutaneous wound healing."Chem Eng J. 2021 Jan;403:126387

• 27. [IF=13.273] Yuxiang Sun et al."Coronal relay reactor Fe3O4@CeO2 for accelerating ROS axial conversion through enhanced Enzyme-like effect and relay effect."Chem Eng J. 2022 Feb;429:132303

• 26. [IF=3.218] Zhuhai Chen et al."Highly sensitive electrogenerated chemiluminescence biosensor for galactosyltransferase activity and inhibition detection using gold nanorod and enzymatic dual signal amplification."J Electroanal Chem. 2016 Nov;781:83

• 25. [IF=6.331] Wenying Li et al."Co3O4 nanocrystals as an efficient catalase mimic for the colorimetric detection of glutathione."J Mater Chem B. 2018 Oct;6(42):6858-6864

• 24. [IF=6.986] Yue Zhao et al."Detection of Various Biomarkers and Enzymes via a Nanocluster-Based Fluorescence Turn-on Sensing Platform."Anal Chem. 2018;90(24):14578–14585

• 23. [IF=7.711] Zhen Zhang et al."Mitochondria-Accessing Ratiometric Fluorescent Probe for Imaging Endogenous Superoxide Anion in Live Cells and Daphnia magna."Acs Sensors. 2018;3(3):735–741

• 22. [IF=9.229] Yunsu Ma et al."A Ratiometric Fluorescence Universal Platform Based on N, Cu Codoped Carbon Dots to Detect Metabolites Participating in H2O2-Generation Reactions."Acs Appl Mater Inter. 2017;9(38):33011–33019

• 21. [IF=10.618] Zonghua Wang et al."Multiple signal amplification electrogenerated chemiluminescence biosensors for sensitive protein kinase activity analysis and inhibition."Biosens Bioelectron. 2015 Jun;68:771

• 20. Zhuang X-C, Chen G-L, Liu Y, Zhang Y-L, Guo M-Q. New Lignanamides with Antioxidant and Anti-Inflammatory Activities Screened Out and Identified from Warburgia ugandensis Combining Affinity Ultrafiltration LC-MS with SOD and XOD Enzymes. Antioxidants. 2021;

• 19. Ma, Yunsu, et al. "A ratiometric fluorescence universal platform based on N, Cu codoped carbon dots to detect metabolites participating in H2O2-generation reactions." ACS applied materials & interfaces 9.38 (2017): 33011-33019.https://doi.org/10.1021/acsam

• 18. Xu, Lian-Hua, et al. "ATMP-induced three-dimensional conductive polymer hydrogel scaffold for a novel enhanced solid-state electrochemiluminescence biosensor." Biosensors and Bioelectronics 143 (2019): 111601.https://doi.org/10.1016/j.bios.2019.111601

• 17. Li, Wenying, et al. "Co 3 O 4 nanocrystals as an efficient catalase mimic for the colorimetric detection of glutathione." Journal of Materials Chemistry B 6.42 (2018): 6858-6864.https://doi.org/10.1039/C8TB01948G

• 16. Lu, Qiaoyun, et al. "Dual-emission reverse change ratio photoluminescence sensor based on a probe of nitrogen-doped Ti3C2 quantum dots@ DAP to detect H2O2 and xanthine." Analytical chemistry 92.11 (2020): 7770-7777.https://doi.org/10.1021/acs.analchem.0c00

• 15. Wu, Zhao‐Yu, et al. "Evaluation of xanthine oxidase inhibitory activity of flavonoids by an online capillary electrophoresis‐based immobilized enzyme microreactor." Electrophoresis 41.15 (2020): 1326-1332.https://doi.org/10.1002/elps.202000083

• 14. Liu, Yongjie, et al. "Inhibition and molecular mechanism of diosmetin against xanthine oxidase by multiple spectroscopies and molecular docking." New Journal of Chemistry 44.17 (2020): 6799-6809.https://doi.org/10.1039/D0NJ00679C

• 13. Pang, Minxia, et al. "Gypenosides inhibits xanthine oxidoreductase and ameliorates urate excretion in hyperuricemic rats induced by high cholesterol and high fat food (lipid emulsion)." Medical science monitor: international medical journal of experimental

• 12. Zhang, Zhen, et al. "Mitochondria-accessing ratiometric fluorescent probe for imaging endogenous superoxide anion in live cells and Daphnia magna." ACS sensors 3.3 (2018): 735-741.http://pubs.acs.org/page/copyright/permissions.html.

• 11. 马倩,赵品成,卢永昌.木藤蓼不同提取部位抑制黄嘌呤氧化酶活性研究[J].中国民族民间医药,2020,29(15):16-20.

• 10. 钟英英,周佳明,叶美凤,何湘惠,邢韩寒,叶云.辣木叶提取物对黄嘌呤氧化酶活性的抑制[J].食品工业,2020,41(11):55-58.

• 9. 王垚. 具有潜在降尿酸能力乳酸菌的筛选及应用研究[D].扬州大学,2021.

• 8. 杨静文,刘泽畅,陈培,杜伟栋,范效兰,石铭,刘玉梅.啤酒花中不同比例β-酸同系物的抗氧化及抑菌活性[J].食品科学,2020,41(23):83-90.

• 7. 邓宝琴, 邹峥嵘. 无患子总皂苷的还原法脱色工艺研究[J]. 江西师范大学学报(自然科学版), 2019, 43(01):94-99.

• 6. 于俊俊, 徐德平. 枳椇子降尿酸功效成分[J]. 食品科技, 2019, v.44;No.337(11):234-238+244.

• 5. 李晶,刘雯,陈超,虞金宝.车前三个不同部位中主要化学成分含量差异及其黄嘌呤氧化酶体外抑制作用比较[J].实用中西医结合临床,2018,18(07):174-176.

• 4. 马倩, 赵品成, 卢永昌. 木藤蓼不同提取部位抑制黄嘌呤氧化酶活性研究[J]. 中国民族民间医药, 2020(15).

• 3. 王静莹, 薄海波, 吉生军,等. 高效液相色谱法快速测定青海牛羊肉和内脏组分中尿酸和嘌呤[J]. 肉类研究, 2017, 31(005):40-45.

• 2. 陈林林, 李伟, 韩可,等. 柠檬叶精油的抗氧化活性及其相关性分析[J]. 中国调味品, 2019, 44(03):52-56.

• 1. 奚春蕊, 包海蓉, 刘琴,等. 基于金枪鱼K值变化的MTT快速传感器的研究及响应面设计[J]. 食品工业科技, 2013, 034(012):131-136.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *