• 介绍：

   Bafilomycin A1 (BafA1) 是特异性，可逆的 V-ATPase 抑制剂，IC₅₀ 值为 4-400 nmol/mg。Bafilomycin A1，大环内酯类抗生素， 是一种自噬 (autophagy) 晚期阶段抑制剂。Bafilomycin A1 阻断自噬体与溶酶体的融合，并抑制培养细胞溶酶体中的酸化和蛋白质降解。Bafilomycin A1 也诱导调亡 (apoptosis)。

• 溶解性： DMSO  :  100  mg/mL  (160.56  mM;  Need  ultrasonic)
  
  H2O  :  <  0.1  mg/mL  (ultrasonic;warming;heat  to  60°C)  (insoluble)

• 敏感性： 对热和光敏感

• 储存条件： -20℃

• 用途： A macrolide antibiotic and potent and selective inhibitor of vacuolar-type (v-type) H+ ATPase

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 5. [IF=5.9] Zekun Zhou et al."Molecular Mechanism of Calycosin Inhibited Vascular Calcification."Nutrients.2024 Jan;16(1):99

• 4. [5.913] Huang Xiaoping et al."Reactive oxygen species enhance rAAV transduction by promoting its escape from late endosomes."Virology Journal.2023 Dec;20(1):1-17

• 3. [IF=3.056] Y. Liu et al."A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome."Neuroscience. 2014 Dec;281:88

• 2. Y. Liu, W. Duan, Y. Guo, Z. Li, H. Han, S. Zhang, P. Yuan, C. Li, A new cellular model of pathological TDP-43: The neurotoxicity of stably expressed CTF25 of TDP-43 depends on the proteasome, Neuroscience, Volume 281, 2014, Pages 88-98, ISSN 0306-4522, htt

• 1. Zhou, Junpei, et al. "Characterization of a NaCl-tolerant β-N-acetylglucosaminidase from Sphingobacterium sp. HWLB1." Extremophiles 20.4 (2016): 547-557.https://doi.org/10.1007/s00792-016-0848-4

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *