• 介绍：

   Captopril (SQ 14225) 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂 (IC50=0.025 μM)，广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是 NDM-1 抑制剂，IC50 值为 7.9 μM。

• 熔点： 104-108°C

• 沸点： 427.043°C at 760 mmHg

• 比旋光度： -129.5 º (c=1, EtOH)

• 外观： 白色或类白色结晶性粉末

• 溶解性： DMSO  :  ≥  50  mg/mL  (230.11  mM)
  
  H2O  :  ≥  50  mg/mL  (230.11  mM)

• 敏感性： 对空气敏感

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 17. [2.8] Kunlin He et al."Magnetic molecularly imprinted polymer based on coordination for the determination of trace banned substance furosemide in human urine."JOURNAL OF SEPARATION SCIENCE.2024 Jul;47(14):2400003

• 16. [IF=5.6] Tao Zeng et al."Rosmarinic acid alleviates septic acute respiratory distress syndrome in mice by suppressing the bronchial epithelial RAS-mediated ferroptosis."INTERNATIONAL IMMUNOPHARMACOLOGY".2024 Jun;135:112304

• 15. [IF=7.9] Jinqiu Rao et al."Unraveling the enigma: Molecular mechanisms of berberrubine-induced nephrotoxicity reversed by its parent form berberine."PHYTOMEDICINE".2024 Jul;129:155648

• 14. [IF=7.5] Hongbo Teng et al."Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis."BIOMEDICINE & PHARMACOTHERAPY

• 13. [IF=5] Meng Chen et al."1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway."EUROPEAN JOURNAL OF PHARMACOLOGY.2023 Sep;954:175863

• 12. [IF=3.614] Kunlin He et al."Magnetic molecularly imprinted polymer based on dynamically established metal-mediated binding sites for the determination of trace captopril in rat plasma."JOURNAL OF SEPARATION SCIENCE.2023 May;:2300092

• 11. [IF=3.757] Lai Xingfei et al."Properties of ACE inhibitory peptide prepared from protein in green tea residue and evaluation of its anti-hypertensive activity."Process Biochem. 2020 May;92:277

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• 8. [IF=5.275] Sui-Qun Yang et al."Separation and configurational assignment of stereoisomeric phenalenones from the marine mangrove-derived fungus Penicillium herquei MA-370."Bioorg Chem. 2021 Jan;106:104477

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• 3. Lai Xingfei, Pan Shunshun, Zhang Wenji, Sun Lingli, Li Qiuhua, Chen Ruohong, Sun Shili, Properties of ACE inhibitory peptide prepared from protein in green tea residue and evaluation of its anti-hypertensive activity, Process Biochemistry, Volume 92, 2020,

• 2. 王宁丽, 魏鉴腾, 王勇,等. 海地瓜血管紧张素转换酶抑制肽体外评价[J]. 食品科技, 2017(9):224-226.

• 1. 李鑫 张琦 赵莹莹 等. 卡托普利脉冲片的制备及处方优化[J]. 药学研究 2018 37(09):25-28.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *