• 介绍：

   Pyrazinamide (Pyrazinecarboxamide; Pyrazinoic acid amide) 是一种有效的口服抗结核类抗生素 (antitubercular antibiotic)。Pyrazinamide 是一种前药，通过结核分枝杆菌 pncA 基因编码的 PZase/烟酰胺酶转化为活性吡嗪酸 (POA) 形式。

   

• 熔点： 189-191°C

• 沸点： 229.19°C (rough estimate)

• 外观： 透明至灰白色结晶粉末

• 溶解性： DMSO  :  ≥  50  mg/mL  (406.14  mM)
  
  H2O  :  6.67  mg/mL  (54.18  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 5. [4.1] Xiaoxiao Liang et al."Supramolecular self-assembly strategy for the enhanced solubility/dissolution rate and anti-cancer efficacy of osimertinib: Insights from multi-component crystals to drug chemistry."CHEMICAL ENGINEERING SCIENCE.2024 Nov;299:120520

• 4. [10.383] Weiqi Liu et al."Functional System Based on Glycyrrhizic Acid Supramolecular Hydrogel: Toward Polymorph Control, Stabilization, and Controlled Release."ACS Applied Materials & Interfaces.2023;XXXX(XXX):XXX-XXX

• 3. [IF=5.215] Jin-Yu Gong et al."Magnesium Isoglycyrrhizinate Attenuates Anti-Tuberculosis Drug-Induced Liver Injury by Enhancing Intestinal Barrier Function and Inhibiting the LPS/TLRs/NF-κB Signaling Pathway in Mice."Pharmaceuticals.2022 Sep;15(9):1130

• 2. [IF=4.098] Jie Liang et al."Deep learning aided quantitative analysis of anti-tuberculosis fixed-dose combinatorial formulation by terahertz spectroscopy."Spectrochim Acta A. 2022 Mar;269:120746

• 1. [IF=2.363] Li Xie et al."A sensitive EZMTT method provides microscale, quantitative and high-throughput evaluation of drug efficacy in the treatment of Mycobacterium tuberculosis infectious diseases."J Microbiol Meth. 2021 Feb;181:106136

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *