• 熔点： >250 °C

• 沸点： 1020.3°C at 760 mmHg

• 外观： 黄色粉末

• 溶解性： 可溶于水，乙醇、甲醇。

• 敏感性： 易吸潮

• 储存条件： -20℃，充氮保存

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 101. [3.7] Mingxin Guo et al."Pharmacological Components and Mechanism Research on the Treatment of Myelosuppression after Chemotherapy with Danggui Jixueteng Decoction Based on Spectrum-Effect Relationships and Transcriptome Sequencing."ACS Omega.2024;9(26):28926–2

• 100. [6.2] Ying Ren et al."Effect of CeO2, TiO2 and SiO2 nanoparticles on the growth and quality of model medicinal plant Salvia miltiorrhiza by acting on soil microenvironment."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jul;280:116552

• 99. [4.8] Qingquan Li et al."Identification of Senkyunolide I as a novel modulator of hepatic steatosis and PPARα signaling in zebrafish and hamster models."JOURNAL OF ETHNOPHARMACOLOGY.2025 Jan;336:118743

• 98. [4.8] Yan Chen et al."Targeting RhoA Expression with Formononetin and Salvianolic acid B to Mitigate Pancreatic Cancer-Associated Endothelial Cells Changes."JOURNAL OF ETHNOPHARMACOLOGY.2024 Aug;:118711

• 97. [6.7] Ziyuan Zhao et al."Pretreatment with Dan-Shen-Yin granules alleviates ethanol-induced gastric mucosal damage in rats by inhibiting oxidative stress and apoptosis via Akt/Nrf2 signaling pathway."PHYTOMEDICINE.2024 Jul;:155866

• 96. [IF=2.6] Fan Yang et al."Preliminary Exploration of Potential Active Ingredients and Molecular Mechanisms of Yanggan Yishui Granules for Treating Hypertensive Nephropathy Using UPLC-Q-TOF/MS Coupled with Network Pharmacology and Molecular Docking Strategy."Journal

• 95. [IF=5.6] Tong Qingheng et al."Integrated chemical characterization, metabolite profiling, and pharmacokinetics analysis of Zhijun Tangshen Decoction by UPLC-Q/TOF-MS."Frontiers in Pharmacology".2024 Mar;15:

• 94. [IF=9.8] Ying Ren et al."Response of antioxidant activity, active constituent and rhizosphere microorganisms of Salvia miltiorrhiza to combined application of microbial inoculant, microalgae and biochar under Cu stress."SCIENCE OF THE TOTAL ENVIRONMENT".2024 May;9

• 93. [IF=1.1] Ji-Yong FU et al."Simultaneous determination of 19 constituents in the Jian-Nao-Ning mixture using high-performance liquid chromatography-tandem mass spectrometry."Separation Science Plus".2024 Feb;:2300222

• 92. [IF=4.6] Jian Zhang et al."Screening of Acetylcholinesterase Inhibitors by Capillary Electrophoresis with Oriented-Immobilized Enzyme Microreactors Based on Gold Nanoparticles."MOLECULES.2024 Jan;29(1):118

• 91. [IF=5.6] Shiyuan Jiang et al."Triptolide attenuates CCL4-induced liver fibrosis by regulating the differentiation of CD4+ T cells in mice."INTERNATIONAL IMMUNOPHARMACOLOGY.2023 Dec;125:111206

• 90. [IF=5.4] Yingqiu Shi et al."Effective constituents and protective effect of Mudan granules against Schwann cell injury."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117692

• 89. [IF=1.6] Nie Lanlan et al."Inhibitory effects and mechanisms of low-temperature plasma on hypertrophic scar."AIP Advances.2023 Dec;13(12):

• 88. [IF=2.8] Minli Yan et al."The potential effect of salvianolic acid B against rat ischemic brain injury in combination with mesenchymal stem cells."JOURNAL OF CHEMICAL NEUROANATOMY.10.1016/j.jchemneu.2023.102338

• 87. [6.449] Chaogeng Lyu et al."A field trials-based study reveals the effects of chlormequat chloride on the quality of medicinal plant Salvia miltiorrhiza Bge. (Lamiaceae) in practical cultivation."INDUSTRIAL CROPS AND PRODUCTS.2023 Apr;194:116396

• 86. [IF=3.246] Guo-Ping Wang et al."To Analyze the Mechanism of SalB Regulating SIRT1 to Inhibit NLRP3 and Its Ameliorative Effect on Tubulogastric Junction Tumor Lesions Complicated with Myocardial Injury."Biomed Research International.2022 Oct 14;2022:6560693

• 85. [IF=2.755] Li Qingju et al."Salvianolic Acid B Alleviates Myocardial Ischemia Injury by Suppressing NLRP3 Inflammasome Activation via SIRT1-AMPK-PGC-1α Signaling Pathway."Cardiovascular Toxicology.2022 Jul;:1-16

• 84. [IF=2.464] Zhou Huifen et al."Pharmacokinetic-Pharmacodynamic Modeling of Active Components from Salvia miltiorrhiza (Danshen) and Carthamus tinctorius (Honghua) in Focal Cerebral Ischemia Rats."Revista Brasileira de Farmacognosia-Brazilian Journal of Pharmacognosy.

• 83. [IF=3.935] Yaqing Guo et al."An integrated strategy for the systematic chemical characterization of Salvianolate lyophilized injection using four scan modes based on the ultra-high performance liquid chromatography-triple quadrupole-linear ion trap mass spectrometry.

• 82. [IF=6.598] Peng Lu et al."Salvianolic acid B dry powder inhaler for the treatment of idiopathic pulmonary fibrosis."Asian Journal of Pharmaceutical Sciences. 2022 Apr;:

• 81. [IF=11.614] Yanqiu Gu et al."In situ synthesis and unidirectional insertion of membrane proteins in liposome-immobilized silica stationary phase for rapid preparation of microaffinity chromatography."Acta Pharmaceutica Sinica B. 2022 Apr;:

• 80. [IF=9.078] Jun Qian et al."A strategy for effective recovery of salvianolic acid a from Salvia miltiorrhiza (Danshen) through multiple interactions."Compos Part B-Eng. 2022 Feb;231:109563

• 79. [IF=5.875] Yutong Wang et al."Extra virgin olive oil-based phospholipid complex/self-microemulsion enhances oral absorption of salvianolic acid B through inhibition of catechol-O-methyltransferase-mediated metabolism."Int J Pharmaceut. 2022 Jan;611:121330

• 78. [IF=7.848] Mingyue Zhou et al."Oriented Layered Graphene Oxide Pad Favoring High Loading Capacity and Stability for High-Throughput Chemical Screening."Advanced Materials Technologies. 2022 Mar 11

• 77. [IF=1.885] Cao Weiyi et al."Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS."Int J Anal Chem. 2021;2021:6620868

• 76. [IF=2.1] Yang Hu et al."Salvianolic acid B alleviates myocardial ischemic injury by promoting mitophagy and inhibiting activation of the NLRP3 inflammasome."Mol Med Rep. 2020 Dec;22(6):5199-5208

• 75. [IF=3.411] Liu Hongyan et al."Effect Study of Continuous Monoculture on the Quality of Salvia miltiorrhiza Bge Roots."Biomed Res Int. 2020;2020:4284385

• 74. [IF=3.765] Shun Liu et al."Simultaneous determination of seven effective components in Shenkui Tongmai granules based on UHPLC-MS/MS."J Pharm Pharmacol. 2021 Apr;73(6):758-766

• 73. [IF=4.074] Jia Li et al."Omics and Transgenic Analyses Reveal that Salvianolic Acid B Exhibits its Anti-Inflammatory Effects through Inhibiting the Mincle-Syk-Related Pathway in Macrophages."J Proteome Res. 2021;XXXX(XXX):XXX-XXX

• 72. [IF=4.162] Weixin Hou et al."The Jieduan-Niwan (JDNW) Formula Ameliorates Hepatocyte Apoptosis: A Study of the Inhibition of E2F1-Mediated Apoptosis Signaling Pathways in Acute-on-Chronic Liver Failure (ACLF) Using Rats."Drug Des Dev Ther. 2021; 15: 3845–3862

• 71. [IF=4.36] Jing Chen et al."Salvianolic acid B and ferulic acid synergistically promote angiogenesis in HUVECs and zebrafish via regulating VEGF signaling."J Ethnopharmacol. 2021 Sep;:114667

• 70. [IF=4.432] Dong Wang et al."Salvianolic acid B attenuates oxidative stress-induced injuries in enterocytes by activating Akt/GSK3β signaling and preserving mitochondrial function."Eur J Pharmacol. 2021 Oct;909:174408

• 69. [IF=4.759] Junjie Feng et al."An integrated data filtering and identification strategy for rapid profiling of chemical constituents, with Arnebiae Radix as an example."J Chromatogr A. 2020 Oct;1629:461496

• 68. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625

• 67. [IF=4.759] Lu-lu Xu et al."Rapid quantitation and identification of the chemical constituents in Danhong Injection by liquid chromatography coupled with orbitrap mass spectrometry."J Chromatogr A. 2019 Nov;1606:460378

• 66. [IF=5.753] Yaping Xiang et al."Integrative Omics Analyses Reveal the Effects of Copper Ions on Salvianolic Acid Biosynthesis."Front Plant Sci. 2021; 12: 746117

• 65. [IF=5.81] Jun Li et al."Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish."Front Pharmacol. 2020; 11: 622787

• 64. [IF=6.529] Weiyi Cao et al."Drug-drug interactions between salvianolate injection and aspirin based on their metabolic enzymes."Biomed Pharmacother. 2021 Mar;135:111203

• 63. [IF=2.943] Zheng Chunli et al."System-level multi-target drug discovery from natural products with applications to cardiovascular diseases."Mol Divers. 2014 Aug;18(3):621-635

• 62. [IF=3.049] Jixia Wang et al."Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay."Rsc Adv. 2015 Mar;5(33):25768-25776

• 61. [IF=3.205] Xianhua Zhang et al."Pharmacokinetic study of representative anti-oxidative compounds from Denshen-Chuanxiong-Honghua following oral administration in rats."J Chromatogr B. 2017 May;1052:82

• 60. [IF=3.845] Zhang Xianhua et al."Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds."Front Pharmacol. 2017 Jul;0:452

• 59. [IF=3.845] Zhang Xianhua et al."Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds."Front Pharmacol. 2017 Jul;0:452

• 58. Wang, Jixia, et al. "Discovery of new targets of phenolic acids in danshen using a label-free cell phenotypic assay." RSC Advances 5.33 (2015): 25768-25776.https://doi.org/10.1039/C4RA16102E

• 57. Zhang, Xianhua, et al. "Danshen-Chuanxiong-Honghua ameliorates cerebral impairment and improves spatial cognitive deficits after transient focal ischemia and identification of active compounds." Frontiers in pharmacology 8 (2017): 452.

• 56. Zhang, Xianhua, et al. "Danshen-Chuanxiong-Honghua ameliorates cerebral impairment and improves spatial cognitive deficits after transient focal ischemia and identification of active compounds." Frontiers in pharmacology 8 (2017): 452.

• 55. Hu, Y., Wang, X., Li, Q., Pan, Y., Xu, L."Salvianolic acid B alleviates myocardial ischemic injury by promoting mitophagy and inhibiting activation of the NLRP3 inflammasome". Molecular Medicine Reports 22.6 (2020): 5199-5208.https://doi.org/10.3892/mmr.20

• 54. Li J, Liu H, Yang Z, Yu Q, Zhao L, Wang Y. Synergistic Effects of Cryptotanshinone and Senkyunolide I in Guanxinning Tablet Against Endogenous Thrombus Formation in Zebrafish. Front Pharmacol. 2021;11:622787. Published 2021 Jan 14. doi:10.3389/fphar.2020.6

• 53. Cao, Weiyi, et al. "Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS." International Journal of Analytical Chemistry 2021 (2021).

• 52. 乐世俊,王文晓,高欢,任继国,付瑞嘉,李佳佳,陈艳琰,唐于平.HPLC同时测定不同厂家丹七片中多个有效成分的含量[J].药物分析杂志,2020,40(12):2236-2243.

• 51. 高瑞琳,杨鹏硕,许刚,武晓文,杨畅,史新元.基于系统建模思想的脑心通胶囊中丹酚酸B近红外定量建模[J].光谱学与光谱分析,2020,40(11):3573-3578.

• 50. 王立,李沐谣,孙斯桐,张文君,吕江唯,崔闻宇.基于渗透压原理的丹酚酸B控释胶囊的制备及释放机制研究[J].中南药学,2021,19(02):198-202.

• 49. 叶淑青,伍清萍,郑雨君,许启龙,邹雨岑,李存玉,董政起.基于临界分离效应的复杂溶液环境中丹酚酸B、苦参碱纳滤分离规律[J].中成药,2021,43(02):314-320.

• 48. 何珊,付先军,张玲,彭霄,王振国.响应面法优化丹参有效成分的提取工艺及其体外抗氧化活性研究[J].中华中医药学刊,2021,39(01):28-32+266-267.

• 47. 李建成,冯斌.丹酚酸B对金黄色葡萄球菌肺炎幼年小鼠肺组织修复及脑神经保护作用的观察[J].郑州大学学报(医学版),2021,56(01):102-108.

• 46. 崔伟亮. 丹参酒炙前后HPLC指纹图谱色谱峰归属比较[J]. 辽宁中医杂志, v.46;No.507(08):1707-1709.

• 45. 郑文华, 奚亚亚, 曲丛丛,等. 酒丹参标准汤剂的质量评价. 中国实验方剂学杂志.

• 44. 黄赵刚, 程钢, 汤浩,等. 血必净注射液指纹图谱研究[J]. 中国医院药学杂志, 2018, 038(022):2323-2327.

• 43. 王芸, 陈军峰, 张磊,等. 基于"有效成分-性状"的关联分析评价丹参品质的研究[J]. 世界科学技术:中医药现代化, 2019(5):835-843.

• 42. 彭九嫚, 柴尧, 潘旻,等. 丹参中酚酸类成分在不同工艺条件下转化关系[J]. 中国实验方剂学杂志, 2016, 022(005):67-70.

• 41. 赵志国, 段文娟, 张晓梦,等. HPLC-DAD-ESI-TOF/MS鉴别和测定前列欣胶囊中多种成分及其多指标定量指纹图谱研究[J]. 药物分析杂志, 2017, 037(010):1810-1816.

• 40. 王闯, 刘廷岳. 离子交换纤维静态吸附丹酚酸B的热力学研究[J]. 北京化工大学学报(自然科学版), 2012(06):17-22.

• 39. 夏天一, 束畅, 孙渺,等. 益气醒脑饮的质量标准改进[J]. 中国医院药学杂志, 2017, 037(023):2364-2367.

• 38. 柳云,任红旗,王增慧,杨阳,戴德淑,刘翔,胡雪晴,李向阳,刘瀛,汤仁仙.甘西鼠尾草总酚酸提取物对嘌呤霉素氨基核苷诱导损伤的足细胞中Toll样受体4表达的影响[J].中国中西医结合肾病杂志,2017,18(08):672-675.

• 37. 吴妍, 耿魁魁, 史天陆,等. 注射用丹参多酚酸盐成品输液的稳定性[J]. 安徽医药, 2018, 22(6):1203-1206.

• 36. 黄娟, 丘小惠, 白俊其,等. 根茎类药材丹参精准煮散饮片的质量评价[J]. 中国实验方剂学杂志, 2017, 023(011):18-22.

• 35. 吴妍, 耿魁魁, 邓晓媚,等. 改进HPLC法测定注射用丹参多酚酸盐中丹酚酸B的含量[J]. 中国药房, 2016(36).

• 34. 李翠, 尉广飞, 李佳,等. 性状异常丹参的利用价值研究[J]. 山东科学, 2014, 27(002):39-43.

• 33. 易丽娟, 李雅, 柳兰,等. 心痛泰颗粒HPLC指纹图谱研究[J]. 中草药, 2019, v.50;No.657(22):95-100.

• 32. 李正, 潘万芳, 朱立明,等. 基于物质流分析的丹红注射液制药过程质量控制研究[J]. 天津中医药大学学报, 2015, 34(06):349-352.

• 31. 易丽娟, 李雅, 邹苏兰,等. 基于正交试验设计与BP神经网络优化益气活血方水提工艺研究[J]. 中草药, 2019, v.50;No.653(18):50-57.

• 30. 石功德, 周静, 李敏,等. 基于R语言的益气活血方药中丹酚酸B提取工艺研究[J]. 中国中医急症, 2017(10):13-15+19.

• 29. 王艺璇 李海涛 刘顺 等. 参葵通脉颗粒的质量标准研究[J]. 中药新药与临床药理 2020年31卷8期 984-989页 ISTIC PKU CSCD CA 2020.

• 28. 白一丹 乔洲 薛敬伟 等. 参松养心胶囊多组分同时测定及方法学验证[J]. 药物分析杂志 2018 v.38(08):80-90.

• 27. 李清清 张继芬. 冠心宁中14种成分的含量测定[J]. 苏盐科技 2019 046(006):33-35.

• 26. 杜秋 谭宁 陆洋 等. 丹酚酸B液晶纳米粒在体鼻吸收及体外血脑屏障细胞吸收研究[J]. 中华中医药杂志 2017 032(007):3140-3143.

• 25. 郭鄂平 杨树国 张珍 等. 丹酚酸B抗小鼠日本血吸虫病肝纤维化的实验研究[J]. 现代预防医学 2014 41(19):3562-3565.

• 24. 陈曾凤 罗涛.丹酚酸B抑制TLR2/NF-κB改善大鼠类风湿性关节炎的作用研究[J].河北医药 2019 41(05):765-767.

• 23. 朱元美 尹步金 张旭 等. 丹酚酸B对高糖诱导的肾小球系膜细胞表型转化及细胞外基质分泌的影响[J]. 中国病理生理杂志 2019 35(02):248-252.

• 22. 郭鄂平 杨树国 张珍 等. 丹酚酸B对小鼠日本血吸虫病肝纤维化MMP-1 TIMP-1的影响[J]. 陕西医学杂志 2014 000(003):259-261.

• 21. 杜秋 杜守颖 李鹏跃 等. 丹酚酸B大鼠在体鼻循环吸收研究[J]. 中国中药杂志 2016 41(002):303-308.

• 20. 刘培 付君秋 邵铁梅 焦展 李雪 仵陶 安胜军.丹酚酸B和丹参酮ⅡA对大鼠胸主动脉外膜成纤维细胞增殖的影响[J].中国药理学通报 2017 33(07):991-996.

• 19. 杨春梅 曹唯仪 侯俊玲 等. 丹酚酸B、芍药苷和甘草酸复配在大鼠体内的药动学参数研究[J]. 西北药学杂志 2018 33(03):94-99.

• 18. 周惠芬 何昱 艾进超 等. 丹红注射液主要有效成分配伍在脑缺血再灌注大鼠体内的药动学研究[J]. 中草药 2016(20).

• 17. 艾进超 何昱 杨荣兵 等. 丹红注射液中主要有效成分在脑缺血大鼠体内药动学研究[J]. 中草药 2015 46(20):79-84.

• 16. 时洁 耿晓康 SHI 等. 丹参酚酸B对慢性肾炎大鼠的疗效及作用机制研究[J]. 解放军医药杂志 2017 10(v.33;No.218):11-15.

• 15. 尉广飞 李佳 刘谦 等. 丹参根部颜色及其与活性成分含量的相关性研究[J]. 山东农业科学 2015(08):59-62.

• 14. 尉广飞 李翠 刘谦 等. 丹参根部直径与其活性成分含有量间的相关性研究[J]. 中成药 2015 37(008):1780-1784.

• 13. 尉广飞 刘谦 李佳 等. 丹参根部活性成分分布规律研究[J]. 山东科学 2015 28(05):7-13.

• 12. 何银舟 胡正明 潘旻 嵇晶 程建明.丹参总酚酸滴丸的制备及质量评价[J].中成药 2019 41(10):2319-2323.

• 11. 宋基正 李凌军 孙鹏 等. 丹参总酚酸双向调节酪氨酸酶机制及大孔树脂分离丹酚酸B研究[J]. 中南药学 2016(4):402-406.

• 10. 王国军 张琳成 陈冰 张宇燕 孔俐 韩进.丹参中丹酚酸B对脑缺血再灌注损伤大鼠的保护作用研究[J].中华中医药学刊 2019 37(07):1566-1568.

• 9. 梁从莲 张永清 李佳 等. 不同株系丹参有效成分比较研究[J]. 山东科学 2018(4):31-38.

• 8. 冯思念 王瑞 顾雯 等. 不同强度的红蓝光质对丹参根系形态和有效成分积累的影响[J]. 中草药 2019(21).

• 7. 石蔚华 赵筱萍 陈晓玲.三叶糖脂清DPP-4抑制成分筛选及其调控JNK/AKT信号通路改善胰岛素抵抗的机制研究[J].浙江中医药大学学报 2019 43(01):7-13.

• 6. 闫妍 石磊 史宁 郭宏举 耿帅 温彬宇.UPLC-Q-TOF-MS同时测定天王补心片中丹参的主要成分[J].解放军药学学报 2018 34(01):55-57.

• 5. 杨春梅 曹唯仪 林珈好 等. SPG复方主要成分配伍给药在大鼠体内药动学参数研究[J]. 辽宁中医药大学学报 2018 020(010):32-35.

• 4. 敏敏 赵志国 刘伟 等. HPLC-DAD法同时测定三种来源丹参饮片中水溶性和脂溶性成分[J]. 山东科学 2019(6).

• 3. 黄翔 何昱 杨洁红 等. HPLC-DAD法与UV-VIS法对丹红注射液有效成分和有效部位的质量控制研究[J]. 中华中医药杂志 2013 028(004):1066-1070.

• 2. 柳兰 李雅 郭志华 易丽娟 邹苏兰 郭紫妍.Box-Behnken响应面法结合G1-熵权法的理气活血复方浸膏喷雾干燥工艺研究[J].中草药 2019 50(11):2560-2566.

• 1. 牛敏 刘红燕 刘谦 等. 4个栽培年限丹参颜色与9种活性成分含量的相关性[J]. 中成药 2017(1):131-135.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *