• 介绍：

  Baicalin 作为一种类黄酮糖苷，是一种变构肉碱棕榈酰转移酶1 (CPT1)是激活剂。Baicalin 降低 NF-KB表达。

• 熔点： 202-205°C

• 沸点： 836.6 °C at 760 mmHg

• 比旋光度： -85°(C=1, DMSO)

• 外观： 淡黄色结晶粉末

• 溶解性： DMSO  :  ≥  100  mg/mL  (224.03  mM)
  
  H2O  :  0.1  mg/mL  (0.22  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 147. [IF=3.3] Li Li et al."Baicalin promotes antiviral IFNs production and alleviates type I IFN-induced neutrophil inflammation."Journal of Natural Medicines.2023 Jul;:1-11

• 146. [IF=4.3] Bao-Fei Yan et al."Huangqin decoction alleviates lipid metabolism disorders and insulin resistance in nonalcoholic fatty liver disease by triggering Sirt1/NF-κB pathway."WORLD JOURNAL OF GASTROENTEROLOGY.2023 Aug 21; 29(31): 4744–4762

• 145. [IF=6] Shuai Yan et al."Baicalin Suppresses Colorectal Cancer Cell Proliferation, Potentially via ARRDC4: Bioinformatics and Experimental analysis."Arabian Journal of Chemistry.2023 Jul;:105141

• 144. [IF=5.2] Guo Huanyu et al."The combined effect of a novel formula of herbal extracts on bacterial infection and immune response in Micropterus salmoides."Frontiers in Microbiology.2023 Jun;14:

• 143. [IF=5.4] Miaomiao Liu et al."Qingjin Huatan decoction protects mice against influenza a virus pneumonia via the chemokine signaling pathways."JOURNAL OF ETHNOPHARMACOLOGY.2023 Dec;317:116745

• 142. [IF=7.5] Jingwen Yuan et al."Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis."BIOMEDICINE & PHARMACOTHERAPY.2023 Aug;164:114986

• 141. [IF=3.976] Su Jianqing et al."Pharmacokinetic Studies of Hyperoside-2-hydroxypropyl-β-cyclodextrin Inclusion Complex and It Ameliorated DSS-Induced Colitis in Mice."BIOSCIENCE REPORTS.2023 May;:

• 140. [IF=4.221] Xixi Fan et al."Baicalin inhibits the replication of the hepatitis B virus by targeting TRIM25."Journal of Traditional and Complementary Medicine.2023 May;:

• 139. [IF=6.388] Jialing Sun et al."Baicalin inhibits hepatocellular carcinoma cell growth and metastasis by suppressing ROCK1 signaling."PHYTOTHERAPY RESEARCH.2023 May;:

• 138. [IF=9.965] Junxiao Zhu et al."Are all poorly soluble drugs dissolved in deep eutectic solvents true solutions?."JOURNAL OF COLLOID AND INTERFACE SCIENCE.2023 Sep;645:813

• 137. [IF=2.139] Y Zhang et al."Baicalin alleviates silica-induced lung inflammation and fibrosis by inhibiting TLR4/NF-?B pathway in rats."PHYSIOLOGICAL RESEARCH.2023 Apr 30;72(2):221-233

• 136. [IF=2.742] Li Mengyuan et al."Baicalin can enhance odonto/osteogenic differentiation of inflammatory dental pulp stem cells by inhibiting the NF-κB and β-catenin/Wnt signaling pathways."MOLECULAR BIOLOGY REPORTS.2023 Apr;:1-12

• 135. [9.429] Su Wenting et al."An intravitreal-injectable hydrogel depot doped borneol-decorated dual-drug-coloaded microemulsions for long-lasting retina delivery and synergistic therapy of wAMD."JOURNAL OF NANOBIOTECHNOLOGY.2023 Dec;21(1):1-19

• 134. [3.246] Yue Qian et al."A Network Pharmacology Method Combined with Molecular Docking Verification to Explore the Therapeutic Mechanisms Underlying Simiao Pill Herbal Medicine against Hyperuricemia."Biomed Research International.2023;2023:2507683

• 133. [4.927] Bingyu Shen et al."Baicalin Relieves LPS-Induced Lung Inflammation via the NF-κB and MAPK Pathways."MOLECULES.2023 Jan;28(4):1873

• 132. [7.419] Mengli Li et al."Baicalin mitigates hypertension-linked alterations in the intestinal lymphatic vasculature in part through preserving the functional barrier integrity of lymphatic endothelial cells."BIOMEDICINE & PHARMACOTHERAPY.2023 Apr;160:114418

• 131. [2.586] Jiaxin Yin et al."Comprehensive multicomponent characterization and quality assessment of Shuang-Huang-Lian powder injection using ultra-high-performance liquid chromatography-quadrupole time-of-flight-mass spectrometry and ultra-high-performance liquid c

• 130. [4.831] Jing Sun et al."Fourier transform infrared spectroscopic markers of the scorching degree of Scutellariae Radix related to the variation patterns of flavonoids and carbohydrates."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2023 Apr;2

• 129. [3.318] Hui Luo et al."Efficacy identification and active compounds screening of topically administration of Scutellaria Radix in oral ulcer."JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES.2022 Dec;:123571

• 128. [5.195] Bao-Fei Yan et al."Huangqin decoction mitigates hepatic inflammation in high-fat diet-challenged rats by inhibiting TLR4/NF-κB/NLRP3 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Mar;303:115999

• 127. [6.525] Xingxing Dai et al."Diammonium Glycyrrhizinate-Based Micelles for Improving the Hepatoprotective Effect of Baicalin: Characterization and Biopharmaceutical Study."Pharmaceutics.2023 Jan;15(1):125

• 126. [5.195] Xiaojing Wang et al."Gegen Qinlian decoction activates AhR/IL-22 to repair intestinal barrier by modulating gut microbiota-related tryptophan metabolism in ulcerative colitis mice."JOURNAL OF ETHNOPHARMACOLOGY.2022 Nov;:115919

• 125. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

• 124. [IF=5.195] Xin Deng et al."A novel strategy for active compound efficacy status identification in multi-tropism Chinese herbal medicine (Scutellaria baicalensis Georgi) based on multi-indexes spectrum-effect gray correlation analysis."JOURNAL OF ETHNOPHARMACOLOGY.20

• 123. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

• 122. [IF=2.721] Haipeng Feng et al."Antiviral activity and underlying mechanisms of Baicalin against avian infectious bronchitis virus in vitro."AVIAN PATHOLOGY

• 121. [IF=5.988] Qihan Luo et al."Chang qing formula ameliorates colitis-associated colorectal cancer via suppressing IL-17/NF-κB/STAT3 pathway in mice as revealed by network pharmacology study."Frontiers in Pharmacology.2022; 13: 893231

• 120. [IF=6.212] Fei Huang et al."Discovery of conversion driven by β-glucuronidase from flavone glycoside to aglycone and application in identifying the raw Scutellariae Radix."Arabian Journal of Chemistry.2022 Aug;:104216

• 119. [IF=3.322] Dongjiu Zhao et al."Baicalin promotes antibacterial defenses by modulating mitochondrial function."BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS.2022 Sep;621:130

• 118. [IF=5.195] Mengmeng Song et al."Homeostatic regulation of the aryl hydrocarbon receptor-cytochrome P450 1a axis by Scutellaria baicalensis-Coptis chinensis herb pair and its main constituents."JOURNAL OF ETHNOPHARMACOLOGY.2022 Jul;:115545

• 117. [IF=8.025] Ying Wang et al."Inhibitory activities of flavonoids from Scutellaria baicalensis Georgi on amyloid aggregation related to type 2 diabetes and the possible structural requirements for polyphenol in inhibiting the nucleation phase of hIAPP aggregation."INT

• 116. [IF=3.935] Yizhu Wang et al."Effects of Scutellaria baicalensis Georgi. on Intestinal Flora in Rats with Spleen Deficiency and Damp-heat."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2022 May;:114831

• 115. [IF=5.095] Liu Fengjie et al."Baicalin-loaded folic acid-modified albumin nanoparticles (FA-BSANPs/BA) induce autophagy in MCF-7 cells via ROS-mediated p38 MAPK and Akt/mTOR pathway."Cancer Nanotechnol. 2022 Dec;13(1):1-21

• 114. [IF=4.072] He Pang et al."Baicalin induces apoptosis and autophagy in human osteosarcoma cells by increasing ROS to inhibit PI3K/Akt/mTOR, ERK1/2 and β-catenin signaling pathways."J Bone Oncol. 2022 Apr;33:100415

• 113. [IF=3.205] Wanli Ji et al."Revealing therapeutic targets and mechanism of baicalin for anti-chronic gastritis using proteomic analysis of the gastric tissue."J Chromatogr B. 2022 Mar;:123214

• 112. [IF=2.193] Zhang Haibo et al.Systematic Study on a Quantitative Analysis of Multicomponents by Single Marker (QAMS) Method for Simultaneous Determination of Eight Constituents in Pneumonia Mixture by UPLC-MS/MS.J Anal Methods Chem. 2021;2021:8311588

• 111. [IF=4.36] Jiali Zhou et al.The root extract of Scutellaria baicalensis Georgi promotes β cell function and protects from apoptosis by inducing autophagy.J Ethnopharmacol. 2022 Feb;284:114790

• 110. [IF=1.625] Hong-Jing Sun et al."Baicalin Alleviates Age-Related Macular Degeneration via miR-223/NLRP3-Regulated Pyroptosis."Pharmacology. 2020;105(1-2):28-38

• 109. [IF=1.851] Rui Li et al."Baicalin inhibits influenza virus A replication via activation of type I IFN signaling by reducing miR‑146a."Mol Med Rep. 2019 Dec;20(6):5041-5049

• 108. [IF=1.913] Zheng XP et al."Kidney-targeted baicalin-lysozyme conjugate ameliorates renal fibrosis in rats with diabetic nephropathy induced by streptozotocin.."Bmc Nephrol. 2020 May;21(1):174-174

• 107. [IF=2.193] Xue Gen et al."Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA."J Anal Methods Chem. 2021;2021:9991363

• 106. [IF=2.193] Xu Tong et al."A Preferable Approach for the Quality Control of Xiaoer Chiqiao Qingre Granules Based on the Combination of Chromatographic Fingerprints and Chemometrics."J Anal Methods Chem. 2020;2020:6836981

• 105. [IF=2.877] Wanli Ji et al."Identifying the active compounds and mechanism of action of Banxia Xiexin decoction for treating ethanol-induced chronic gastritis using network pharmacology combined with UPLC–LTQ–Orbitrap MS."Comput Biol Chem. 2021 Aug;93:107535

• 104. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 103. [IF=3.361] Mengmeng Yuan et al."The interaction of dietary flavonoids with xanthine oxidase in vitro: molecular property-binding affinity relationship aspects."Rsc Adv. 2019 Apr;9(19):10781-10788

• 102. [IF=3.882] Kunpeng Yin et al."Lanthanide Metal–Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine."Langmuir. 2021;37(17):5321–5328

• 101. [IF=3.935] Zhengchao Ji et al."Global identification and quantitative analysis of representative components of Xin-Nao-Kang Capsule, a traditional Chinese medicinal formula, by UHPLC-Q-TOF-MS and UHPLC-TQ-MS."J Pharmaceut Biomed. 2021 May;198:114002

• 100. [IF=3.935] Meng Chen et al."Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate."J Pharmaceut Biomed. 2021 Feb;195:113820

• 99. [IF=3.935] Chenglong Sun et al."A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi."J Pharmaceut Biomed. 2020 Feb;179:113014

• 98. [IF=4.162] Leyi Ma et al."Baicalin Alleviates Oxidative Stress and Inflammation in Diabetic Nephropathy via Nrf2 and MAPK Signaling Pathway."Drug Des Dev Ther. 2021; 15: 3207–3221

• 97. [IF=4.225] Wu Dandan et al."Baicalin Protects Against Hypertension-Associated Intestinal Barrier Impairment in Part Through Enhanced Microbial Production of Short-Chain Fatty Acids."Front Pharmacol. 2019 Oct;0:1271

• 96. [IF=4.545] Xiangyan Wu et al."Qingda granules attenuate hypertensive cardiac remodeling and inflammation in spontaneously hypertensive rats."Biomed Pharmacother. 2020 Sep;129:110367

• 95. [IF=4.759] Yi Zhang et al."Screening of inhibitors against histone demethylation jumonji domain-containing protein 3 by capillary electrophoresis."J Chromatogr A. 2020 Feb;1613:460625

• 94. [IF=4.759] Yueping Jiang et al."Application of multifold characteristic ion filtering combined with statistical analysis for comprehensive profiling of chemical constituents in anti-renal interstitial fibrosis I decoction by ultra-high performance liquid chromatogra

• 93. [IF=5.11] Xiaonan Liu et al."De Novo Biosynthesis of Multiple Pinocembrin Derivatives in Saccharomyces cerevisiae."Acs Synth Biol. 2020;9(11):3042–3051

• 92. [IF=5.246] Sui Xinbing et al."Baicalin Induces Apoptosis and Suppresses the Cell Cycle Progression of Lung Cancer Cells Through Downregulating Akt/mTOR Signaling Pathway."Front Mol Biosci. 2021 Jan;0:323

• 91. [IF=5.279] Yanan Gao et al."Galactosylation of Monosaccharide Derivatives of Glycyrrhetinic Acid by UDP-Glycosyltransferase GmSGT2 from Glycine max."J Agr Food Chem. 2020;68(32):8580–8588

• 90. [IF=5.34] Shihao Yan et al."Network pharmacology-based identification of significant pathway for protection of Yinhuang granule in a mice model of metabolic-associated fatty liver disease."Phytomedicine. 2021 Oct;91:153666

• 89. [IF=5.81] Cui Lihua et al."Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway."Front Pharmacol. 2021 Jun;0:1369

• 88. [IF=5.81] Zhenyu Fan et al."Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis."Front Pharmacol. 2021; 12: 628988

• 87. [IF=5.833] Zhou Zhidu et al."Ultra-sensitive amperometric determination of quercetin by using a glassy carbon electrode modified with a nanocomposite prepared from aminated graphene quantum dots, thiolated β-cyclodextrin and gold nanoparticles."Microchim Acta. 2020

• 86. [IF=5.875] Yumei Wu et al."Brain targeting of Baicalin and Salvianolic acid B combination by OX26 functionalized nanostructured lipid carriers."Int J Pharmaceut. 2019 Nov;571:118754

• 85. [IF=6.17] Liang Shi et al."Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation."Free Radical Bio Med. 2020 Nov;160:163

• 84. [IF=9.381] Ya Zhao et al."Polysaccharide from vinegar baked radix bupleuri as efficient solubilizer for water-insoluble drugs of Chinese medicine."Carbohyd Polym. 2020 Feb;229:115473

• 83. [IF=3.205] Xianhua Zhang et al."Pharmacokinetic study of representative anti-oxidative compounds from Denshen-Chuanxiong-Honghua following oral administration in rats."J Chromatogr B. 2017 May;1052:82

• 82. [IF=3.738] Selma Houchi et al."Investigation of common chemical components and inhibitory effect on GES-type β-lactamase (GES22) in methanolic extracts of Algerian seaweeds."Microb Pathogenesis. 2019 Jan;126:56

• 81. [IF=3.845] Zhang Xianhua et al."Danshen-Chuanxiong-Honghua Ameliorates Cerebral Impairment and Improves Spatial Cognitive Deficits after Transient Focal Ischemia and Identification of Active Compounds."Front Pharmacol. 2017 Jul;0:452

• 80. [IF=3.935] Yanqiu Gu et al."Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix."J Pharmaceut Biomed. 2019 Feb;164:550

• 79. [IF=3.935] Ka-Yan Kwok et al."Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatography."J Pharmaceut Biomed. 2013 Nov;85:239

• 78. [IF=4.101] Hai-yan Zhu et al."Baicalin inhibits autophagy induced by influenza A virus H3N2."Antivir Res. 2015 Jan;113:62

• 77. [IF=4.96] Liang Shi et al."Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC."Biochem Pharmacol. 2018 Apr;150:9

• 76. [IF=6.057] Kai Sheng et al."Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin."Talanta. 2017 Mar;164:249

• 75. [IF=6.529] Liliqiang Ding et al."Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats."Biomed Pharmacother. 2019 Mar;111:325

• 74. Chen, Meng, et al. "Comprehensive analysis of Huanglian Jiedu decoction: Revealing the presence of a self-assembled phytochemical complex in its naturally-occurring precipitate." Journal of Pharmaceutical and Biomedical Analysis 195 (2021): 113820.https://

• 73. Xu, Jun. "Improved approaches and strategies for analyzing decoctions of medicinal herbs." (2016).

• 72. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164

• 71. Cheng, Yan, et al. "Controlled Extraction of Flavonoids From Radix Scutellariae by Subcritical Water." CLEAN–Soil, Air, Water 44.3 (2016): 299-303.https://doi.org/10.1002/clen.201300193

• 70. Sun, Chenglong, et al. "A spatially-resolved approach to visualize the distribution and biosynthesis of flavones in Scutellaria baicalensis Georgi." Journal of pharmaceutical and biomedical analysis 179 (2020): 113014.https://doi.org/10.1016/j.jpba.2019.11

• 69. Shi, Liang, et al. "Baicalein and baicalin alleviate acetaminophen-induced liver injury by activating Nrf2 antioxidative pathway: The involvement of ERK1/2 and PKC." Biochemical pharmacology 150 (2018): 9-23.https://doi.org/10.1016/j.bcp.2018.01.026

• 68. Xue, Gen, et al. "Integrating Study on Qualitative and Quantitative Characterization of the Major Constituents in Shuanghuanglian Injection with UHPLC/Q-Orbitrap-MS and UPLC-PDA." Journal of Analytical Methods in Chemistry 2021 (2021).https://doi.org/10.11

• 67. Sui, Xinbing, et al. "Baicalin induces apoptosis and suppresses the cell cycle progression of lung cancer cells through downregulating Akt/mTOR signaling pathway." Frontiers in Molecular Biosciences 7 (2021): 323.https://doi.org/10.3389/fmolb.2020.602282

• 66. Zhu, Hai-yan, et al. "Baicalin inhibits autophagy induced by influenza A virus H3N2." Antiviral research 113 (2015): 62-70.https://doi.org/10.1016/j.antiviral.2014.11.003

• 65. Shi, Liang, et al. "Baicalin promotes liver regeneration after acetaminophen-induced liver injury by inducing NLRP3 inflammasome activation." Free Radical Biology and Medicine 160 (2020): 163-177.https://doi.org/10.1016/j.freeradbiomed.2020.05.012

• 64. Wu, Dandan, et al. "Baicalin protects against hypertension-associated intestinal barrier impairment in part through enhanced microbial production of short-chain fatty acids." Frontiers in pharmacology 10 (2019): 1271.https://doi.org/10.3389/fphar.2019.0127

• 63. Ding, Liliqiang, et al. "Baicalin relaxes vascular smooth muscle and lowers blood pressure in spontaneously hypertensive rats." Biomedicine & Pharmacotherapy 111 (2019): 325-330.https://doi.org/10.1016/j.biopha.2018.12.086

• 62. G. Qi, A. Liu, Z. Liu and Z. Bai, "A Novel HPLC Method for Determining Three Effective Components in Chinese Medicine 'Xiao' Erjiebiao Granules," 2012 International Conference on Biomedical Engineering and Biotechnology, 2012, pp. 16-20, doi: 10.1109/iCBEB

• 61. Sheng, Kai, et al. "Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin." Talanta 164 (2017): 249-256.https://doi.org/10.1016/j.talanta.2016.11.050

• 60. Sheng, Kai, et al. "Green synthesized Co nanoparticles doped amino-graphene modified electrode and its application towards determination of baicalin." Talanta 164 (2017): 249-256.https://doi.org/10.1016/j.talanta.2016.11.050

• 59. 刘萍,唐代,王旭,白云.黄芩苷对心肌缺血再灌注损伤的保护作用机制[J].中医药学报,2021,49(02):16-21.

• 58. 黄芳,孙亚宁,常克,冯丹丹,王志强.黄芩苷对低氧诱导的新生大鼠肺损伤的保护作用[J].中国药理学与毒理学杂志,2020,34(10):736-742.

• 57. 唐君,杜杨,赵凤娇,崔勐,刘志强.电喷雾串联质谱研究黄芩苷与谷胱甘肽的相互作用[J].应用化学,2021,38(03):331-342.

• 56. 林珊,陈达鑫,蔡巧燕,张铃,陈静雯,李金艳,彭军,褚剑锋.UPLC法测定清达颗粒和清眩降压汤中黄芩苷的含量[J].福建中医药,2021,52(03):30-32.

• 55. 邓远雄,胡剑卓,佘成烨,李静.高脂血症大鼠灌胃黄连解毒汤后黄芩苷的药代动力学研究[J].中南药学,2020,18(12):1986-1991.

• 54. 李壮壮, 张静, 赵绍哲,等. 指纹图谱与化学计量学结合优选柴胡桂枝颗粒水提工艺[J]. 中成药, 2018, v.40(08):199-203.

• 53. 姜万舟, 高平, 杨明德,等. 杏鲍菇乙醇提取物的抗氧化活性及成分分离鉴定[J]. 食品工业科技, 2015, 36(22):87-91.

• 52. 杨梦玲, 尤朋涛, 何丽珊,等. 基于UPLC-MS/MS分析胃溃疡模型大鼠口服加味小柴胡颗粒后血浆中8种有效成分的药代动力学[J]. 中国中药杂志, 2018, 43(18).

• 51. 陈智. 金银花和黄芩不同煎煮方式化学成分变化及抗病毒作用比较[J]. 中华中医药杂志, 2019, v.34(10):129-133.

• 50. 张静 李壮壮 杜宝香 等. HPLC法同时测定柴胡桂枝汤中6种成分[J]. 中成药 2018 040(010):2202-2205.

• 49. 李云静, 张建逵, 赵玥,等. 黄芩药材颜色及其有效成分的相关性[J]. 中国医药工业杂志, 2017(7).

• 48. 吴贵才, 赵丹, 曾青磊,等. 黄芩苷诱导人乳腺癌细胞株MCF-7凋亡的机制研究[J]. 中国医药科学, 2017, 7(005):14-18.

• 47. 杨洁, 李日婵. 黄芩苷抑制H5N1禽流感病毒进入的机制研究[J]. 天然产物研究与开发, 2016, v.28(02):98-102.

• 46. 范景辉, 赵玉梅, 张颖,等. 黄芩苷对糖尿病合并非酒精脂肪肝大鼠血脂和肝功能的影响观察[J]. 中国现代医生, 2020(9):29-31.

• 45. 吴峰淼,叶凯丽,刘曦.黄芩苷对大鼠胶原诱导性关节炎JAK/STAT3信号通路及Th17/Treg免疫平衡的影响[J].中国药师,2020,23(02):246-251.

• 44. 何志坚, 胜海峰, 刘海云. 黄芩苷对大鼠放射性肺损伤的保护作用[J]. 实用癌症杂志, 2018, v.33;No.199(10):5-8.

• 43. 马双, 宋鹏琰, 韩超,等. 黄芩苷对双酚A致小鼠生殖损伤的保护作用[J]. 中国兽医学报, 2018, 038(009):1753-1760.

• 42. 马宗敏, 刘佳, 段绪红,等. 黄芩苷发酵转化成黄芩素和千层纸素A的黄芩内生真菌的筛选及鉴定[J]. 中国实验方剂学杂志, 2019(9):166-171.

• 41. 徐治中,竺平,周寄文,杨柏霖.黄芩苷促使细胞G2/M阻滞抑制错配修复基因缺失的结直肠癌裸鼠原位移植瘤生长[J].中药药理与临床,2017,33(02):24-28.

• 40. 何谷良, 袁娉, 黄家望,等. 黄芩苷体外对耐甲氧西林金黄色葡萄球菌活性影响的研究[J]. 时珍国医国药, 2019(4).

• 39. 郭净洁, 王崇, 张维甲,等. 黄芩素与黄芩苷联合用药对口腔鳞癌细胞增殖,迁移的影响[J]. 口腔医学, 2020, 040(005):393-398.

• 38. 顿佳颖, 李佳佳, 郑鹏,等. 黄芩汤传统汤剂与配方颗粒中3种有效成分的比较研究[J]. 中医药导报, 2019, 25(05):78-81+89.

• 37. 程燕, 曲绍风, 李福伟,等. 黄芩中4种黄酮类化合物的亚临界水提取研究[J]. 山东科学, 2013(03):11-14.

• 36. 山光强, 陈志刚, 许广人,等. 金樱子总黄酮的含量测定及酶提工艺优化[J]. 中国畜牧兽医, 2016, 43(012):3156-3162.

• 35. 何原, 黄石安, 陈灿,等. 进口与国产黄芩苷对低氧性肺动脉平滑肌细胞增殖影响的比较[J]. 广东医学, 2016, 37(010):1433-1436.

• 34. 陈海君, 马尚智, 江敏,等. 超滤亲和-液质联用和分子对接技术筛选毛菊苣根中α-葡萄糖苷酶抑制剂[J]. 中草药, 2019, 50(02):85-92.

• 33. 宗春燕, 苏学军, 梁雅娟. 超声浸渍法提取木蝴蝶中总黄酮的工艺研究[J]. 化学工程师, 2019, 33(02):18-20.

• 32. 李蒙蒙,田小杏,马丽娟,蒲晓辉,袁琦,宗兰兰,徐颖峰.薄层色谱法鉴别三黄片中的有效成分[J].河南大学学报(医学版),2016,35(02):81-84+109.

• 31. 谭丽丽,杨向方,李燕广,张国徽.缺血预处理联合黄芩苷预处理对大鼠脑缺血再灌注半暗带细胞凋亡及Bcl-2/Bax比值的影响[J].中西医结合心脑血管病杂志,2014,12(02):220-221.

• 30. 董浩浩, 李从举. 离子交换纤维吸附黄芩苷的动力学与热力学研究[J]. 西南师范大学学报(自然科学版), 2014, 000(001):7-14.

• 29. 李纳,李姣娇,范蕾,陈章宝.用山银花与金银花制备双黄连口服液质量比较研究[J].西北药学杂志,2018,33(01):6-10.

• 28. 尹丽, 张潇菡, 马丽娟,等. 牛黄解毒片的显微鉴别及薄层鉴别[J]. 河南大学学报(医学版), 2016(2):85-88.

• 27. 郭允, 陈永超, 李晓花,等. 牛黄解毒片中6种指标成分的含量测定[J]. 沈阳药科大学学报, 2016(6):454-458.

• 26. 林珊, 张铃, 蔡巧燕,等. 清眩降压汤对离体大鼠胸主动脉的舒张作用及黄芩苷成分分析[J]. 福建中医药, 2018, 049(001):34-36.

• 25. 李玲云,王云,刘梦娇,张雪,李晓庆,戴业佳,麻印莲,张村.栀子金花丸化学成分的UPLC-Q-TOF-MS/MS快速鉴定与分析[J].中国实验方剂学杂志,2017,23(14):1-11.

• 24. 杨爽, 何妍茜, 杨洁,等. 感冒软胶囊质量标准提高的研究[J]. 时珍国医国药, 2013, 24(008):1930-1932.

• 23. 余欢欢, 黄启迪, 颜美秋,等. 孕康口服液3种成分测定及HPLC指纹图谱建立[J]. 中成药, 2020, v.42(03):46-51.

• 22. 刘媛媛, 刘陶, 吴玉梅,等. 基于雌激素受体调节Nrf2-ARE通路的黄芩中抗氧化成分的筛选[J]. 中国药理学通报, 2019, 035(006):822-827.

• 21. 袁杰, 李锬, 周利,等. 基于超高效液相色谱法和色差仪法的黄芩药材质量评价[J]. 世界中医药, 2019.

• 20. 商利娜, 王亚静, 赵鑫,等. 基于谱-效关系探究黄芩抑制白色念珠菌的质量标志物[J]. 中成药, 2020, 042(005):1357-1361.

• 19. 柴冲冲,曹妍,毛民,王靖越,刘娜,李欣欣,张凯,陈东玲,魏龙吟,尹怡慧,李飞.基于电子舌技术评价黄芩酒炙前后滋味变化及其在黄芩饮片鉴别中的应用研究[J].中国中药杂志,2020,45(11):2552-2559.

• 18. 刘艳, 杨炳友, 孙艳,等. 基于活性和Plackett-Burnman联合Box-Behnken设计的复方栀子金花提取工艺优化[J]. 中华中医药杂志, 2019, 34(04):69-73.

• 17. 张建逵,李云静,孙智,王冰,康廷国.基于断面色泽测定的条芩饮片分级研究[J].中国中药杂志,2017,42(21):4115-4119.

• 16. 任永申, 邓鑫, 雷蕾,等. 基于抑菌效应成分指纹谱的黄芩质量评价研究[J]. 药学学报, 2019, 054(012):2155-2161.

• 15. 李淑娇, 王宇卿. 基于HPLC-Q-TOF/MS法的黄芩血清药物化学分析[J]. 中成药, 2019, 41(03):117-122.

• 14. 侯广玉 李孟全 赵鹏程 王一成 朱立双 杜书迪.咳尔康颗粒对肺腺癌细胞A549的体外抗肿瘤作用[J].医药导报 2019 38(01):27-32.

• 13. 陈慧洁 杨亚楠 丁辉 等. 养阴利咽半生制剂袋泡茶的制备及优化[J]. 天津中医药大学学报 2019 38(01):78-83.

• 12. 万鹏 赵瑞芝 胡巧红. 中药多糖对黄芩苷的溶解度及其药动学的影响[J]. 广东药学院学报 2017(4).

• 11. 秦书芝 李凤 张瑶 等. 不同软化处理方法对黄芩饮片中黄芩苷含量影响[J]. 海峡药学 2017(10):30-31.

• 10. 柴冲冲 毛民 袁金凤 等. 不同方法软化切制后的黄芩饮片颜色与5种黄酮类成分含量的相关性研究[J]. 中国中药杂志 2019.

• 9. 杨强 蒲晓辉 李晓花. 一清胶囊中7种指标成分的测定[J]. 华西药学杂志 2017(3).

• 8. 范汇森 闫秋莹 张海彬 等. UPLC-MS/MS法测定大鼠血浆中紫草氰苷 格列风内酯浓度简[J]. 南京中医药大学学报 2018(1):91-95.

• 7. 康宁芳 李梅 胡贺佳 肖红琴 刘利琴 李银 李月婷 王爱民 王永林 张昀 何峰 巩仔鹏.UPLC-MS/MS同时测定舒肝宁注射液在大鼠血浆中4种活性成分的含量及其药代动力学研究[J].中国中药杂志 2020 45(11):2626-2633.

• 6. 刘阿静 齐广才 刘珍叶 等. RP—HPLC法测定防风通圣丸中芍药苷 栀子苷 黄芩苷和连翘苷的含量[J]. 西北药学杂志 2012 27(5):415-415.

• 5. 郝乘仪 张慧锋 杨明慧. RP-HPLC法同时测定小儿肺热咳喘颗粒中两种主要活性成分的含量[J]. 吉林医药学院学报 2017(1).

• 4. 李晓花 郭允 李佳 袁琦 蒲晓辉 王高峰.RP-HPLC法同时测定三黄片中7种指标成分的含量[J].沈阳药科大学学报 2016 33(08):637-642.

• 3. 张宏梅 昌盛 崔佰吉 等. HPLC法同时测定茵胆平肝胶囊中6种成分的含量[J]. 中国药房 2017年28卷9期 1239-1242页 ISTIC PKU CA 2017 28(9):1239-1242.

• 2. 吴宇锋 陈灵哲 林忠. HPLC法同时测定3种煎法下防风通圣方中的黄芩苷和栀子苷含量[J]. 上海医药 2018 v.39;No.493(01):64-67.

• 1. 王东超 魏颖 高佳琪 孙文 秦灵灵 兰卫 石浩霞 李博 徐暾海 刘铜华.HPLC同时测定糖痹康颗粒中黄芩苷、汉黄芩苷、黄芩素、汉黄芩素的含量[J].吉林中医药 2017 37(05):513-517.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *