雷公藤甲素 HPLC≥98%

Triptolide

源叶
B20709
38748-32-2
C20H24O6
360.4
MFCD00210565
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶 B20709-20mg HPLC≥98% ¥750.00元 >10 3 - 5
源叶 B20709-100mg HPLC≥98% ¥1872.00元 >10 1 2 -
产品介绍 参考文献(65篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

熔点: 226-227°C
沸点: 601.7 °C at 760 mmHg
比旋光度: D25 -154°
外观: 白色或微黄的结晶
溶解性: 难溶于水,溶于甲醇、乙酸乙酯、氯仿等。
储存条件: 2-8℃
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(65篇)

60. [IF=14.7] Lai Wang et al."A rationally designed CD19 monoclonal antibody-triptolide conjugate for the treatment of systemic lupus erythematosus."Acta Pharmaceutica Sinica B.2024 Sep;: 59. [IF=4.8] Li Qiang et al."Novel Detoxifier of Spironolactone Against Triptolide-induced Hepatotoxicity through Inhibition of RPB1 Degradation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Aug;:118722 58. [IF=6.5] Zhe Li et al."Homotypic cell membrane-camouflaged biomimetic PLGA nanoparticle loading triptolide for the treatment of hepatocellular carcinoma."DRUG DELIVERY. 57. [IF=6.1] Qiao-Lei Wang et al."Ultrasensitive upconverting nanoprobes for in situ imaging of drug-induced liver injury using miR-122 as the biomarker."TALANTA".2024 Jul;274:126108 56. [IF=2.9] Hanping Liang et al."Triptolide inhibits esophageal squamous cell carcinoma progression by regulating the circNOX4/miR-153-3p/SATB1 signaling pathway."Thoracic Cancer.2024 Jan;: 55. [IF=5.6] Shiyuan Jiang et al."Triptolide attenuates CCL4-induced liver fibrosis by regulating the differentiation of CD4+ T cells in mice."INTERNATIONAL IMMUNOPHARMACOLOGY.2023 Dec;125:111206 54. [IF=5.1] Wang Qian et al."HSP90 Exacerbates Bone Destruction in Rheumatoid Arthritis by Activating TRAF6/NFATc1 Signaling."INFLAMMATION.2023 Oct;:1-13 53. [IF=3.3] Wan Lei et al."A novel pharmaceutical preparation of Tripterygium wilfordii Hook. f. regulates macrophage polarization to alleviate inflammation in rheumatoid arthritis."JOURNAL OF PHARMACY AND PHARMACOLOGY.10.1093/jpp/rgad078 52. [IF=7.9] Zhiyan Qin et al."Mitigation of triptolide-induced testicular Sertoli cell damage by melatonin via regulating the crosstalk between SIRT1 and NRF2."PHYTOMEDICINE.2023 Sep;118:154945 51. [IF=3.222] Chenlei Lv et al."Triptolide protects against podocyte injury in diabetic nephropathy by activating the Nrf2/HO-1 pathway and inhibiting the NLRP3 inflammasome pathway."RENAL FAILURE.2023;45(1):Article: 2165103 50. [IF=9.417] Yunan Zhao et al."Engineering adipocytes for targeting delivery of triptolide derivative and Ce6 for malignant melanoma cytotoxic-PDT synergistic strategy."MATERIALS & DESIGN.2023 Apr;228:111860 49. [IF=2.626] Ma, Rui-jiao et al."Kunxian Capsule Extract Inhibits Angiogenesis in Zebrafish Embryos via PI3K/AKT-MAPK-VEGF Pathway."Chinese Journal of Integrative Medicine.2022 Dec;:1-9 48. [IF=3.685] Guoyao Tan et al."MitoQ alleviates triptolide-induced cardiotoxicity via activation of p62/Nrf2 axis in H9c2 cells."TOXICOLOGY IN VITRO.2023 Feb;86:105487 47. [IF=5.195] Yanqiu Sun et al."Xinfeng capsule inhibits inflammation and oxidative stress in rheumatoid arthritis by up-regulating LINC00638 and activating Nrf2/HO-1 pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jan;301:115839 46. [IF=2.984] Linluo Zhang et al."Protection of catalpol against triptolide-induced hepatotoxicity by inhibiting excessive autophagy via the PERK-ATF4-CHOP pathway."Peerj. 2022 Jan;10:e12759 45. [IF=10.435] Li Zhe et al.Sorafenib and triptolide loaded cancer cell-platelet hybrid membrane-camouflaged liquid crystalline lipid nanoparticles for the treatment of hepatocellular carcinoma.J Nanobiotechnol. 2021 Dec;19(1):1-12 44. [IF=3.411] Zhou Yuyan et al."Arctiin Antagonizes Triptolide-Induced Hepatotoxicity via Activation of Nrf2 Pathway."Biomed Res Int. 2020;2020:2508952 43. [IF=4.617] Li Zhe et al."γ-Cyclodextrin metal–organic framework as a carrier to deliver triptolide for the treatment of hepatocellular carcinoma."Drug Delivery and Translational Research. 2021 Apr 15 42. [IF=5.914] Bo Ma et al."Luteolin Ameliorates Testis Injury and Blood–Testis Barrier Disruption through the Nrf2 Signaling Pathway and by Upregulating Cx43."Mol Nutr Food Res. 2019 May;63(10):1800843 41. [IF=6.419] Yanwen Zheng et al."Membrane protein-chimeric liposome-mediated delivery of triptolide for targeted hepatocellular carcinoma therapy."Drug Deliv. 2021;28(1):2033-2043 40. [IF=6.684] Yi-Sheng Song et al."Validation, Optimization, and Application of the Zebrafish Developmental Toxicity Assay for Pharmaceuticals Under the ICH S5(R3) Guideline."Front Cell Dev Biol. 2021; 9: 721130 39. [IF=9.229] Liangdi Jiang et al."Engineering Exosomes Endowed with Targeted Delivery of Triptolide for Malignant Melanoma Therapy."Acs Appl Mater Inter. 2021;13(36):42411–42428 38. [IF=2.303] Ingrid Elisia et al."Comparison of RAW264.7, human whole blood and PBMC assays to screen for immunomodulators."J Immunol Methods. 2018 Jan;452:26 37. [IF=3.347] Jiamin Kong et al."Triptolide induces mitochondria-mediated apoptosis of Burkitt's lymphoma cell via deacetylation of GSK-3β by increased SIRT3 expression."Toxicol Appl Pharm. 2018 Mar;342:1 36. [IF=3.585] Jie Zhang et al."MitoQ ameliorates testis injury from oxidative attack by repairing mitochondria and promoting the Keap1-Nrf2 pathway."Toxicol Appl Pharm. 2019 May;370:78 35. [IF=5.875] Yongwei Gu et al."Transdermal drug delivery of triptolide-loaded nanostructured lipid carriers: Preparation, pharmacokinetic, and evaluation for rheumatoid arthritis."Int J Pharmaceut. 2019 Jan;554:235 34. [IF=6.4] Li Zhang et al."Fabrication of a triptolide-loaded and poly-γ-glutamic acid-based amphiphilic nanoparticle for the treatment of rheumatoid arthritis."Int J Nanomed. 2018; 13: 2051–2064 33. [IF=10.435] Yang Meng et al."Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics."J Nanobiotechnol. 2017 Dec;15(1):1-15 32. [IF=10.435] Gu Yongwei et al."Lipid nanoparticles loading triptolide for transdermal delivery: mechanisms of penetration enhancement and transport properties."J Nanobiotechnol. 2018 Dec;16(1):1-14 31. Elisia, Ingrid, et al. "Comparison of RAW264. 7, human whole blood and PBMC assays to screen for immunomodulators." Journal of immunological methods 452 (2018): 26-31.https://doi.org/10.1016/j.jim.2017.10.004 30. Shan, Qian-Qian, et al. "Cubic and hexagonal liquid crystals as drug carriers for the transdermal delivery of triptolide." Drug delivery 26.1 (2019): 490-498.https://doi.org/10.1080/10717544.2019.1602796 29. Yang, Meng, et al. "Development of triptolide-nanoemulsion gels for percutaneous administration: physicochemical, transport, pharmacokinetic and pharmacodynamic characteristics." Journal of nanobiotechnology 15.1 (2017): 1-15.https://doi.org/10.1186/s12951 28. Zhang, Jie, et al. "MitoQ ameliorates testis injury from oxidative attack by repairing mitochondria and promoting the Keap1-Nrf2 pathway." 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