• 介绍： Colchicine is a tubulin inhibitor and a microtubule disrupting agent. Colchicine inhibits microtubule polymerization with an IC50 of 3 nM. Colchicine is also a competitive antagonist of the α3 glycine receptors (GlyRs)

• 熔点： 150-160℃

• 比旋光度： (CHCl3)-121

• 外观： 白色粉末

• 溶解性： Soluble  in  DMSO、H2O

• 敏感性： 对光敏感,易吸潮

• 储存条件： 2-8℃

• 用途： Functions by binding to tubulin and arresting cell division at m

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 9. [IF=7.9] Tian Lan et al."Paeoniflorin promotes PPARγ expression to suppress HSCs activation by inhibiting EZH2-mediated histone H3K27 trimethylation."PHYTOMEDICINE".2024 Jun;128:155477

• 8. [IF=6.1] Guangwen Shu et al."Ergothioneine suppresses hepatic stellate cell activation via promoting Foxa3-dependent potentiation of the Hint1/Smad7 cascade and improves CCl4-induced liver fibrosis in mice."Food & Function.2023 Nov;:

• 7. [IF=3.3] Piao Huiqing et al."Ternary Deep Eutectic Solvents System of Colchicine, 4-Hydroxyacetophenone, and Protocatechuic Acid and Characterization of Transdermal Enhancement Mechanism."AAPS PHARMSCITECH.2023 Dec;24(8):1-15

• 6. [IF=7.9] Tingting Qin et al."Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis."PHYTOMEDICINE.2023 Sep;118:154971

• 5. [IF=16.6] Fan Shengjie et al."Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions."Nature Communications.2023 Jun;14(1):1-23

• 4. [6.51] Meng Chen et al."Deuterated colchicine liposomes based on oligomeric hyaluronic acid modification enhance anti-tumor effect and reduce systemic toxicity."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2022 Dec;:122578

• 3. [IF=9.229] Qing-Shan Liu et al."Novel Beta-Tubulin-Immobilized Nanoparticles Affinity Material for Screening β-Tubulin Inhibitors from a Complex Mixture."Acs Appl Mater Inter. 2017;9(7):5725–5732

• 2. 范素芳, 马俊美, 刘茁,等. 高效液相色谱-串联质谱测定食品中15种有毒生物碱[J]. 食品科学, 2018, 39(22):290-295.

• 1. 李培宁 陈秀娟 江漪 等. 3种化合物在UV诱导下对CHL细胞染色体畸变作用[J]. 日用化学工业 2019 49(006):377-380 387.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *