• 介绍：

   Nicotinamide 是维生素 B3 或烟酸的一种形式，可抑制 SIRT2 的体外活性，其 EC50 值为 2 μM。 Nicotinamide 可抑制 90% 的黑色素瘤细胞数量，并增加细胞内 NAD+、ATP、ROS 水平。Nicotinamide 抑制黑色素瘤小鼠的肿瘤生长并提高生存率，可用于黑色素瘤等皮肤癌相关的研究。

• 熔点： 128-131 °C(lit.)

• 沸点： 150-160°C

• 外观： 白色至类白色粉末

• 溶解性： Souble  in  DMSO  ,H2O

• 敏感性： 对光敏感

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 15. [IF=8.2] Yulong Wei et al."New insight into molecular mechanisms of different polyphenols affecting Sirtuin 3 deacetylation activity."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;:132026

• 14. [IF=8.1] Zhaocheng Tang et al."In vitro digestion under simulated saliva, gastric and small intestinal conditions and fermentation of nicotinamide mononucleotide, and its effects on the gut microbiota."FOOD RESEARCH INTERNATIONAL.2023 Nov;:113779

• 13. [IF=5.4] Bo Zhang et al."Integration of single-nucleus RNA sequencing and network disturbance to elucidate crosstalk between multicomponent drugs and trigeminal ganglia cells in migraine."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;319:117286

• 12. [IF=3.6] Su Wu et al."Antidiabetic activity of eupafolin through peroxisome proliferator-activated receptor-gamma and PI3K/Akt signaling in Type 2 diabetic rats."JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY.2023 Aug;:e23463

• 11. [IF=4.7] Guo-Ying Chen et al."Rapid and sensitive detection of alkaline phosphatase and glucose oxidase activity through fluorescence and colorimetric dual-mode analysis based on CuO NPs@ZIF-8 mediated enzyme-cascade reactions."Nanoscale Advances.2023 Aug;:

• 10. [IF=5.2] Meijie Song et al."Enhanced Production of β-Nicotinamide Mononucleotide with Exogenous Nicotinamide Addition in Saccharomyces boulardii-YS01."Foods.2023 Jan;12(15):2897

• 9. [IF=8.025] Guangzhen Zhou et al."Transcriptome and targeted metabolomic integrated analysis reveals mechanisms of B vitamin accumulation in Areca catechu nut development."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Jun;241:124570

• 8. [8.025] Chongyang Zhu et al."A pH-sensitive hydrogel based on carboxymethylated konjac glucomannan crosslinked by sodium trimetaphosphate: Synthesis, characterization, swelling behavior and controlled drug release."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECUL

• 7. [IF=3.645] Aijin Shen et al."Chemical profiling of Qingfei Paidu Decoction by triplex off-line two-dimensional liquid chromatography coupled with quadrupole time-of-flight mass spectrometry."Journal Of Separation Science. 2022 Jan 09

• 6. [IF=3.534] Zhaoyang Zhang et al."Molecular Mechanisms Involved in Supersaturation of Emodin Ternary Solid Dispersions Based on Bonding Agents."J Pharm Sci-Us. 2022 Jan;:

• 5. [IF=2.044] Chen Guo-Ying et al."Immobilized Kallikrein Microreactor Based on Capillary Electrophoresis for Online Enzyme Kinetics Analysis and Inhibitor Screening."Chromatographia. 2021 Oct 11

• 4. [IF=6.953] Chongyang Zhu et al."A pH-sensitive semi-interpenetrating polymer network hydrogels constructed by konjac glucomannan and poly (γ-glutamic acid): Synthesis, characterization and swelling behavior."Int J Biol Macromol. 2021 Aug;185:229

• 3. 邬燕红,胡新成,项琪,陈颖之,贝煜.化妆品中烟酰胺透皮吸收的临床评估[J].香料香精化妆品,2020(04):61-64.

• 2. 吴金平, 杜浩, 陈细华, et al. 烟酸对杂交鲟幼鱼生长性能,肌肉品质和抗氧化功能的影响[J]. 中国水产科学, 2020(4):406-413.

• 1. 邬燕红、胡新成、项琪、陈颖之、贝煜. 化妆品中烟酰胺透皮吸收的临床评估[J]. 香料香精化妆品 2020 No.181(04):67-70.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *