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分析标准品,HPLC≥98%

Captopril

源叶
B24255 一键复制产品信息
62571-86-2
C9H15NO3S
217.29
MFCD00168073
N-[(S)-3-巯基-2-甲基丙酰基]-L-脯氨酸
货号 规格 价格 上海 北京 武汉 南京 购买数量
B24255-100mg 分析标准品,HPLC≥98% ¥135.00 >10 - 2 -
B24255-1g 分析标准品,HPLC≥98% ¥600.00 6 - - -
产品介绍 参考文献(19篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

 Captopril (SQ 14225) 是一种含巯基的口服活性血管紧张素转换酶 (ACE) 抑制剂 (IC50=0.025 μM),广泛应用于高血压和充血性心力衰竭的研究。Captopril 也是 NDM-1 抑制剂,IC50 值为 7.9 μM。

熔点: 104-108°C
沸点: 427.043°C at 760 mmHg
比旋光度: -129.5 º (c=1, EtOH)
外观: 白色或类白色结晶性粉末
溶解性: DMSO  :  ≥  50  mg/mL  (230.11  mM)

H2O  :  ≥  50  mg/mL  (230.11  mM)
敏感性: 对空气敏感
储存条件: 2-8℃
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(19篇)

14. [IF=7.5] Hongbo Teng et al."Design and synthesis of 3,4-seco-lupane triterpene derivatives to resist myocardial ischemia-reperfusion injury by inhibiting oxidative stress-mediated mitochondrial dysfunction via the PI3K/AKT/HIF-1α axis."BIOMEDICINE & PHARMACOTHERAPY 13. [IF=5] Meng Chen et al."1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway."EUROPEAN JOURNAL OF PHARMACOLOGY.2023 Sep;954:175863 12. [IF=3.614] Kunlin He et al."Magnetic molecularly imprinted polymer based on dynamically established metal-mediated binding sites for the determination of trace captopril in rat plasma."JOURNAL OF SEPARATION SCIENCE.2023 May;:2300092 11. [IF=3.757] Lai Xingfei et al."Properties of ACE inhibitory peptide prepared from protein in green tea residue and evaluation of its anti-hypertensive activity."Process Biochem. 2020 May;92:277 10. [IF=3.943] Xi Chu et al."Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro."Int Immunopharmacol. 2020 Jul;84:106548 9. [IF=5.275] Hong-Lei Li et al."Structurally diverse alkaloids produced by Aspergillus creber EN-602, an endophytic fungus obtained from the marine red alga Rhodomela confervoides."Bioorg Chem. 2021 May;110:104822 8. [IF=5.275] Sui-Qun Yang et al."Separation and configurational assignment of stereoisomeric phenalenones from the marine mangrove-derived fungus Penicillium herquei MA-370."Bioorg Chem. 2021 Jan;106:104477 7. [IF=5.279] Yanbo Huang et al."Novel ACE Inhibitory Peptides Derived from Yeast Hydrolysates: Screening, Inhibition Mechanisms and Effects on HUVECs."J Agr Food Chem. 2021;69(8):2412–2421 6. [IF=5.279] Mengdi Chen et al."Novel Umami Peptide IPIPATKT with Dual Dipeptidyl Peptidase-IV and Angiotensin I-Converting Enzyme Inhibitory Activities."J Agr Food Chem. 2021;69(19):5463–5470 5. [IF=7.46] Ying Zhang et al."A polydopamine-polyethyleneimine/quantum dot sensor for instantaneous readout of cell surface charge to reflect cell states."Sensor Actuat B-Chem. 2020 Dec;324:128696 4. Chu, Xi, et al. "Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro." International immunopharmacology 84 (2020): 106548.https://doi.org/10.1016/j.intimp.2020.106548 3. Lai Xingfei, Pan Shunshun, Zhang Wenji, Sun Lingli, Li Qiuhua, Chen Ruohong, Sun Shili, Properties of ACE inhibitory peptide prepared from protein in green tea residue and evaluation of its anti-hypertensive activity, Process Biochemistry, Volume 92, 2020, 2. 王宁丽, 魏鉴腾, 王勇,等. 海地瓜血管紧张素转换酶抑制肽体外评价[J]. 食品科技, 2017(9):224-226. 1. 李鑫 张琦 赵莹莹 等. 卡托普利脉冲片的制备及处方优化[J]. 药学研究 2018 37(09):25-28.

质检证书(COA)

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