吲哚美辛

    
分析标准品,HPLC≥99%

Indomethacin

源叶
B27001 一键复制产品信息
53-86-1
C19H16ClNO4
357.79
MFCD00057095
消炎痛;茚甲新;1-(4-氯苯甲酰基)-5-甲氧基-2-甲基-1H-吲哚-3-乙酸
货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
B27001-250mg 分析标准品,HPLC≥99% ¥180.00 4 1 - 2
产品介绍 参考文献(29篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Indomethacin (Indometacin) 是一种有效的口服活性 COX1/2 抑制剂,COX-1 和 COX-2 的IC50 值分别为 18 nM 和 26 nM。Indomethacin 具有抗癌和抗感染活性。Indomethacin 可用于癌症、炎症和病毒感染的研究。

熔点: 158-162°C
沸点: 499.4ºC at 760 mmHg
外观: 白色至亮黄色结晶
溶解性: DMSO  :  100  mg/mL  (279.49  mM;  Need  ultrasonic)

Ethanol  :  12.5  mg/mL  (34.94  mM;  Need  ultrasonic)

H2O  :  <  0.1  mg/mL  (insoluble)
敏感性: 光敏感
储存条件: 2-8℃
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(29篇)

24. [IF=4.3] Gao Wen-Ya et al."Integrated Phytochemical Analysis Based on Ultra-high-performance Liquid Chromatography-mass Spectrometry and Network Pharmacology Approaches to Explore the Bioactive Constituents and Potential Targets of Jiangtang Qingre Formula."World 23. [IF=3.2] Hao-Dong Yang et al."Identification of lignans as selective cyclooxygenase-2 inhibitors from the extract of Acanthopanacis cortex."PHYTOCHEMISTRY.2024 Oct;226:114208 22. [IF=12.2] Tingting Chai et al."Multidimensional occurrence and diet risk of emerging contaminants in freshwater with urban agglomerations."JOURNAL OF HAZARDOUS MATERIALS.2024 Aug;474:134813 21. [IF=1.6] Wang Bohui et al."Tilapia Head Glycolipid Alleviates Indomethacin-Induced Gastric Ulcer via Regulating Oxidative Stress and Inflammation Through COX/PGE2 Signaling Pathway in Adult Rats."Journal of Ocean University of China".2024 Jun;23(3):743-754 20. [IF=3.4] Hao-Dong Yang et al."Diterpenoids from Acanthopanacis Cortex and their anti-inflammatory activity studies."FITOTERAPIA".2024 Jul;176:106021 19. [IF=4.4] Qinsheng Zheng et al."Unraveling the underlying mechanism of interactions between astaxanthin geometrical isomers and bovine serum albumin."SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY.2024 Mar;308:123731 18. [IF=5.4] Jia Sun et al."Screening of anti-functional dyspepsia compounds in Cynanchum auriculatum: A spectrum-effect relationship analysis, and ATP-binding cassette transporters inhibitor evaluation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Jan;318:116867 17. [IF=5.062] Shouli Wang et al."Evodiamine-loaded rhEGF-conjugated bovine serum albumin nanoparticles alleviate indomethacin-associated gastric mucosal injury in male SD rats."JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY.2023 Mar;:104345 16. [IF=6.656] Yanchao Xing et al."Cytochrome P450-mediated herb-drug interaction (HDI) of Polygonum multiflorum Thunb. based on pharmacokinetic studies and in vitro inhibition assays."PHYTOMEDICINE.2023 Feb;:154710 15. [IF=7.425] Wen-Juan Song et al."Evaluation the food safety of cultured fat via detection of residues of adipogenic differentiation cocktail in cultured fat with high performance liquid chromatography and enzyme-linked immunosorbent assay."FOOD RESEARCH INTERNATIONAL 14. [IF=6.911] Chengyu Yan et al."Monitoring of silica colloidal crystal-embedded chitosan hydrogel films swelling and its drug release application."ANALYTICA CHIMICA ACTA.2022 Dec;1236:340582 13. [IF=3.534] Jiuheng Ruan et al."A Systematic Quantitative Evaluation of Permeation Enhancement Window: Transdermal Permeation Enhancing Dynamics Establishment and Molecular Mechanisms Characterization of Permeation Enhancer."J Pharm Sci-Us. 2022 Jan;: 12. [IF=5.81] Huixia Feng et al."Exploring Multifunctional Bioactive Components from Podophyllum sinense Using Multi-Target Ultrafiltration."Front Pharmacol. 2021; 12: 749189 11. [IF=3.343] Qian Kang et al."Transdermal delivery system of nanostructured lipid carriers loaded with Celastrol and Indomethacin: optimization, characterization and efficacy evaluation for rheumatoid arthritis."Artificial Cells Nanomedicine and Biotechnology. 2018 O 10. [IF=4.545] Hui Yang et al."Intestinal absorption mechanisms of araloside A in situ single-pass intestinal perfusion and in vitro Caco-2 cell model."Biomed Pharmacother. 2018 Oct;106:1563 9. 程佑民,林静瑜,周凡,黄培炜,陈祺,许金森.预针刺结合穴位注射对胃溃疡大鼠胃黏膜的损伤修复作用及机制探讨[J].中国医药科学,2021,11(03):20-24. 8. 毕冉冉 白睿 刘志强 刘惠亮.人诱导多能干细胞来源间充质干细胞与骨髓间充质干细胞的生物学性状比较[J].军事医学 2018 42(12):941-948. 7. 宋炎博 赵贵山 汝晓飞 侯珂 林梦舟 李辛洁 孟庆蓉 王捍东.吲哚美辛人工抗原及其多克隆抗体的制备[J].畜牧与兽医 2019 51(10):44-48. 6. 张永萍, 徐剑, 谢伟杰. 星点设计-效应面法优化吲哚美辛亲水凝胶贴剂基质处方及成型工艺[J]. 医药导报, 2018, 037(005):593-599. 5. 谢伟杰, 张永萍, 徐剑. 均匀设计筛选吲哚美辛亲水凝胶贴剂的基质处方[J]. 中国药房, 2017(10). 4. 李素丽 刘桂卿. 吲哚美辛凝胶剂体外透皮特性的初步研究[J]. 世界最新医学信息文摘 2016(52):154-155. 3. 马兆臣 陈奎奎 李月婷 et al. 丹荷颗粒25种特征性成分LC-MS测定及制剂一致性分析[J]. 中草药 2019 v.50;No.659(24):63-72. 2. 雷雨声 张俊勇 田官强 等. Wnt/β-catenin/TCF-4信号通路调节livin表达在肾癌细胞增殖凋亡中的研究[J]. 重庆医科大学学报 2019 044(006):716-721. 1. 张永萍 徐剑 吴静澜 等. pH对吲哚美辛理化性质和离体透皮参数的影响[J]. 中国药房 2016(34).

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