产品中心

Product center

地塞米松 BR,99%

Dexamethasone

源叶
S17003
50-02-2
C22H29FO5
392.46
MFCD00064136
氟甲去氢氢化可的松;氟美松;9-氟-11,17,21-三羟基-16-甲基(11b,16a)-孕甾-1,4-二烯-3,20-二酮
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶 S17003-1g BR,99% ¥90.00元 10 2 1 4
源叶 S17003-5g BR,99% ¥245.00元 >10 - 2 1
源叶 S17003-25g BR,99% ¥750.00元 >10 - 1 -
源叶 S17003-100g BR,99% ¥2400.00元 4 - - -
产品介绍 参考文献(43篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Dexamethasone是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。在脂多糖诱导的巨噬细胞炎症反应中,它抑制含有炎性 microRNA-155 的外泌体的产生。

熔点: 255-264°C
沸点: 568.2ºC at 760 mmHg
比旋光度: 75 º (c=1, dioxane)
外观: 白色结晶固体
溶解性: DMSO:73  mg/mL  (186  mM)
Ethanol:6  mg/mL  (15.28  mM)
敏感性: 对光和空气敏感
储存条件: 2-8℃
注意: 部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。

参考文献(43篇)

38. [IF=3.1] Faqin Wang et al."Analysis and prediction of immune cell infiltration characteristics in COPD: Folium isatidis and its active ingredients are able to combat lung lesions caused by COPD by correcting immune cell infiltration."Frontiers in Medicine.2025 Apr 37. [IF=2.9] Li Xiang et al."Nobiletin ameliorates hormone-induced osteoblast apoptosis by modulating JAK2/STAT3 signaling."JOURNAL OF MOLECULAR HISTOLOGY.2025 Jun;56(3):1-7 36. [IF=3.8] Guoping Cai et al."NLRP3 blockade by MCC950 suppressed osteoclastogenesis via NF-κB/c-Fos/NFATc1 signal pathway and alleviated bone loss in diabetes mellitus."MOLECULAR AND CELLULAR ENDOCRINOLOGY.2024 Dec;594:112382 35. [IF=6] Mengting Li et al."Design, synthesis, and biological evaluation of oridonin derivatives as novel NLRP3 inflammasome inhibitors for the treatment of acute lung injury."EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.2024 Aug;:116760 34. [IF=2.9] Jingjing Yan et al."The natural sesquiterpene lactone inulicin suppresses the production of pro-inflammatory mediators via inhibiting NF-κB and AP-1 pathways in LPS-activated macrophages."IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY. 33. [IF=1.3] Jing-Yu Zhang et al."Bioactive prenylated c6–c3 derivatives from the roots of Illicium brevistylum."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. 32. [IF=4.7] Wenjing Li et al."Safflower yellow in Carthami Flos is responsible for Xuebijing Injection-induced immediate hypersensitivity reaction through activating complement C3."Chinese Herbal Medicines.2024 Jun;: 31. [IF=3.1] Meng Yan et al."Diammonium Glycyrrhizinate Inhibited Inflammatory Response and Modulated Serum Metabolism in Poly(I:C)-induced Pneumonia Model Mice."SHOCK".2024 Mar;:10.1097/SHK.0000000000002353 30. [IF=5.6] Rong Xu et al."Extracellular ATP contributes to the reactive oxygen species burst and exaggerated mitochondrial damage in D-galactosamine and lipopolysaccharide-induced fulminant hepatitis."INTERNATIONAL IMMUNOPHARMACOLOGY".2024 Mar;130:111680 29. [IF=1.8] Xiaojuan Li et al."Peimine Alleviated Bleomycin-Induced Pulmonary Fibrosis in Mice Through Reducing Epithelial-Mesenchymal Transition, Inflammation and Oxidative Stress and Regulating Host Metabolism."Natural Product Communications.;(): 28. [IF=7.9] Xin-yun-xi He et al."Orcinol glucoside targeted p38 as an agonist to promote osteogenesis and protect glucocorticoid-induced osteoporosis."PHYTOMEDICINE.2023 Oct;119:154953 27. [IF=4.004] Wen-Rui Li et al."Bergamotane-type sesquiterpenes from the leaves and twigs of Illicium oligandrum and their anti-inflammatory activities."PHYTOCHEMISTRY.2023 May;209:113617 26. [IF=6.317] Kun Wang et al."Mechanic study of salidroside on ovalbumin-induced asthmatic model mice based on untargeted metabolomics analysis."Food & Function.2022 Nov;: 25. [IF=2.98] Chen Rui et al."Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway."MOLECULAR GENETICS AND GENOMICS.2022 Jun;:1-11 24. [IF=3.922] Fengling Wang et al."Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo."Drug Metab Dispos. 2019 Aug;47(8):785-793 23. [IF=4.05] Zhi-Yuan Wu et al."Anti-inflammatory Diterpenoids from the Root Bark of Acanthopanax gracilistylus."J Nat Prod. 2014;77(11):2342–2351 22. Mengqiu Lu, Haizhen Liang, Pengfei Tu, Yong Jiang. Pharmacodynamic comparison of two different source plants of Murrayae Folium et Cacumen[J]. Journal of Chinese Pharmaceutical Sciences, 2021, 30(1): 49-57.DOI: 10.5246/jcps.2021.01.005 21. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164 20. Wu, Zhi-Yuan, et al. "Anti-inflammatory diterpenoids from the root bark of Acanthopanax gracilistylus." Journal of natural products 77.11 (2014): 2342-2351.http://pubs.acs.org/page/copyright/permissions.html 19. Wu, Zhi-Yuan, et al. "Anti-inflammatory diterpenoids from the root bark of Acanthopanax gracilistylus." Journal of natural products 77.11 (2014): 2342-2351.124.17.89.23 18. Xu, Ye, et al. "CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats." Acta Pharmacologica Sinica 39.8 (2018): 1386-1392.https://doi.org/10.1038/aps.2017.170 17. Gu, Yanqiu, et al. "Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix." Acta Pharmaceutica Sinica B 10.10 (2020): 1856-186 16. 柏永全,史睿,茹凝玉,马丽蓉,王芙蓉,王文文,陈果.雷公藤红素缓解刀豆蛋白A诱导的小鼠急性肝损伤作用及其机制[J].河南大学学报(自然科学版),2020,50(05):551-559. 15. 王长华,王鑫,沈佚葳,刘凯.紫草素对湿疹小鼠的治疗作用及机制研究[J].中国药师,2021,24(03):456-461. 14. 王文文,柏永全,邓乐乐,宋贞洁,陈果,卢兹凡,翟东昇.水苏碱对葡聚糖硫酸钠诱导的炎性肠病的保护作用及其机制[J].河南大学学报(自然科学版),2021,51(01):48-57. 13. 胡蔚,李岚.枇杷叶提取物对卵清蛋白诱导的哮喘小鼠气道炎症和气道重塑的影响[J].中国现代应用药学,2021,38(01):20-27. 12. 肖卫棉,查旭山,王友发.丹皮酚对湿疹模型小鼠SP、NK1R表达及肥大细胞活化的影响[J].天津医药,2020,48(09):824-828+913-914. 11. 苗延青,尤静,薛鹏燕.柴胡、黄芩、甘草、葛根四种药物颗粒剂与水煎剂抗炎镇痛作用比较[J].医学信息,2020,33(21):73-75. 10. 张东博, 王征, 梁艳妮,等. 青花椒根皮中1个新的香豆素类化合物[J]. 中草药 2019年50卷12期, 2798-2801页, ISTIC PKU CSCD CA, 2019. 9. 徐叶,杜江波,冯慧瑾,左建平,许红涛,李援朝,钟大放.雷公藤甲素衍生物雷腾舒的体外代谢研究[J].药学学报,2019,54(08):1484-1492. 8. 黄洋, 邵慧凯, 李康,等. 小叶榕叶抗炎成分分析及活性评价[J]. 中成药, 2014(06):1227-1233. 7. 黄洋,李康,邵慧凯,刘盛权.小叶榕叶对LPS诱导的RAW264.7巨噬细胞NO和TNF-α的影响[J].中药新药与临床药理,2014,25(02):124-127. 6. 葛瑜,缪华.宣白承气汤调控sirt1/FOXO1通路对脂多糖致大鼠急性肺损伤的影响[J].四川中医,2020,38(07):52-56. 5. 刘珊珊, 向彬, 郭营营,等. 天麻成分对羟基苯甲醛抗炎作用及机制研究[J]. 中国民族民间医药, 2016(9). 4. 李艳, 蒋石, 郭营营,等. 天麻成分对羟基苯甲醇抗实验性脑血栓形成及抗炎作用研究[J]. 昆明医科大学学报, 2015, 036(001):P.28-31. 3. 白隆博, 马逍遥, 常念伟,等. 基于整合网络药理学和化学物质组学的灯台叶片的抗炎作用机制研究[J]. 中草药, 2018, v.49;No.627(16):139-145. 2. 葛淑瑜, 李岚, 孙萍萍. 桑白皮总黄酮对哮喘小鼠气道炎症反应的保护作用. 温州医科大学学报. 1. 毕冉冉 白睿 刘志强 刘惠亮.人诱导多能干细胞来源间充质干细胞与骨髓间充质干细胞的生物学性状比较[J].军事医学 2018 42(12):941-948.

质检证书(COA)

如何获取质检证书(COA)?
请输入货号和一个与之匹配的批号。
例如:
批号:JS298415 货号:S20001-25g
在货品标签上如何找到货号和批号?

摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

=
×
×

相关产品