PS 48

    
98%

(2Z)-5-(4-Chlorophenyl)-3-Phenyl-2-Pentenoicacid

源叶(MedMol)
S26102 一键复制产品信息
1180676-32-7
C17H15ClO2
286.753
(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid; WAY 161503 hydrochloride; 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;
货号 规格 价格 上海 北京 武汉 南京 购买数量
S26102-5mg 98% ¥310.00 5 - - -
S26102-10mg 98% ¥470.00 5 - - -
S26102-25mg 98% ¥710.00 6 - - -
S26102-100mg 98% ¥2040.00 货期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

PS-48 是 phosphoinositide-dependent protein kinase-1 (PDK1) 的变构激活剂

产品描述: PS-48 是 phosphoinositide-dependent protein kinase-1 (PDK1) 的变构激活剂
靶点: PDK1;PDK
体内研究: In vivo, the PDK1 agonist PS48 can maintain the bone mass of mice treated with dexamethasone
细胞实验: Cell lines: MC3T3-E1 cells Concentrations: 5 μM Incubation Time: -- Method: MC3T3-E1 cells are cultured in an osteogenic differentiation medium containing 4 mM glycerophosphate and 25 μg/mL ascorbic acid until 70% confluency. Dexamethasone (final concentration of ethanol, 0.01%, vol/vol) at different concentrations is then added to the osteogenic differentiation medium for 14 days. The culture medium is replaced every two days. MC3T3-E1 cells are cultured in a culture medium containing 10−7 M dexamethasone supplemented with or without PS48 (5 μM).
动物实验: Animal Models: 8-week-old male C57BL/6J mice Dosages: -- Administration: --
参考文献: 1. Valerie Hindie, et al.Nat Chem Biol. 2009 Oct;5(10):758-64. 2. Wen-Ning Xu, et al. Front Endocrinol (Lausanne). 2020 Jan 28;10:922.
溶解性: Soluble  in  DMSO、Ethanol
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.487 ml 17.437 ml 34.873 ml
5 mM 0.697 ml 3.487 ml 6.975 ml
10 mM 0.349 ml 1.744 ml 3.487 ml
50 mM 0.07 ml 0.349 ml 0.697 ml
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参考文献

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摩尔浓度计算器

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