| 产品描述： | Sal003 is a potent, specific and cell-permeable inhibitor of the eukaryotic translation initiation factor 2α (eIF2α) phosphatase. Sal003 is a derivative of salubrinal |
| 靶点： |
eIF2α phosphatase;Apoptosis |
| 体内研究： |
Sal003 (20Μm; intrahippocampal injection; 8 minutes) impairs contextual memory in vivo |
| 参考文献： |
1. Costa-Mattioli M, et al. eIF2alpha phosphorylation bidirectionally regulates the switch from short- to long-term synaptic plasticity and memory. Cell. 2007 Apr 6;129(1):195-206. 2. Yahiro K, et al. Regulation of subtilase cytotoxin-induced cell death by an RNA-dependent protein kinase-like endoplasmic reticulum kinase-dependent proteasome pathway in HeLa cells. Infect Immun. 2012 May;80(5):1803-14. |
| 溶解性： |
DMSO : ≥ 100 mg/mL (215.88 mM) |
| 保存条件： |
2-8℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.163 ml |
10.817 ml |
21.635 ml |
| 5 mM |
0.433 ml |
2.163 ml |
4.327 ml |
| 10 mM |
0.216 ml |
1.082 ml |
2.163 ml |
| 50 mM |
0.043 ml |
0.216 ml |
0.433 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京