产品描述: | Bicyclol(SY 801) is a anti-hepatitis drug. Target: HBV Oral administration of bicyclol normalized the elevated serum transaminases (ALT, AST) by approximately 50% in chronic viral hepatitis B and C, and also showed certain level of inhibiting HBV and HCV replication. No noticeable adverse reaction has been observed. In combination therapy of bicyclol with interferon alpha, lamivudine and adefovir dipivoxil in HBV or HCV, bicyclol may potentiate the anti-viral efficacy and reduce YMDD mutant and side effects. In 2004 China FDA issued license to manufacture bicyclol. Since then bicyclol has been widely used to treat chronic HBV and HCV in China |
靶点: |
HBV;Autophagy |
参考文献: |
1. Walsh, S.W., Y. Wang, and A. Killian, AA-2414, an antioxidant and thromboxane receptor blocker, completely inhibits peroxide-induced vasoconstriction in the human placenta. J Pharmacol Exp Ther, 1999. 290(1): p. 220-6. |
溶解性: |
DMSO : 100 mg/mL (256.19 mM; Need ultrasonic) |
保存条件: |
2-8℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
2.562 ml |
12.809 ml |
25.618 ml |
5 mM |
0.512 ml |
2.562 ml |
5.124 ml |
10 mM |
0.256 ml |
1.281 ml |
2.562 ml |
50 mM |
0.051 ml |
0.256 ml |
0.512 ml |
|
注意: |
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