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Melanotan II acetate salt 98%

Melanotan II acetate salt

源叶(MedMol)
S80172
121062-08-6
C50H69N15O9
1024.18
MFCD06795842
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S80172-1mg 98% ¥255.00元 预计交期:2-3天 - - -
源叶(MedMol) S80172-5mg 98% ¥475.00元 预计交期:2-3天 - - -
源叶(MedMol) S80172-10mg 98% ¥680.00元 预计交期:2-3天 - - -
源叶(MedMol) S80172-50mg 98% ¥1930.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.
产品描述: Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an injectable peptide hormone used to promote tanning.
靶点: Peptides;MelanocortinReceptor
体内研究:
Melanotan (MT)-II exerts a dose-dependent inducer activity on erection by eliciting erectile events and shortening latency of the first erectile event to occur. Erectile responses elicited by cavernous nerve stimulation are increased after i.v. melanotan (MT)-II (1 mg/kg), thereby exerting facilitator effect on erection. Melanotan (MT)-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Melanotan (MT)-II significantly enhances the recovery of sensory function following a crush lesion of the sciatic nerve in the rat at a dose of 20 μg/kg per 48 h, s.c., but not at a dose of 2 or 50 μg/kg. Melanotan (MT)-II is a potent initiator of penile erection in men with erectile dysfunction. Melanotan (MT)-II reduces food intake and body weight and invokes thermogenic responses in a mouse model
参考文献:
1. Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7(2):164-72. 2. Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138(1):293-301. 3. Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83. 4. Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9. 5. De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E644-51.
溶解性: Soluble  in  H2O
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 0.976 ml 4.882 ml 9.764 ml
5 mM 0.195 ml 0.976 ml 1.953 ml
10 mM 0.098 ml 0.488 ml 0.976 ml
50 mM 0.02 ml 0.098 ml 0.195 ml
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参考文献

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