Faropenem sodium

    98%

Faropenem sodium

源叶(MedMol)
S80189
122547-49-3
C12H14NO5S.Na
307.298
法罗培南钠;法罗培南;(+)-(5R,6S)-6-[(R)-1-羟基乙基]-7-氧代-3-[(R)-2-四氢呋喃基]-4-硫杂-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸钠;法罗培南(钠)(二倍半水合物);(+)-(5R,6S)-6-[(R)-1-羟基乙基]-7-氧代-3-[(R)-2-四氢呋喃基]-4-硫杂-1-氮杂双环[3.2.0]庚-2-烯-2-羧酸钠;法罗培南钠;(5r,6s)-6-(
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S80189-5mg 98% ¥210.00元 >10 - - -
源叶(MedMol) S80189-10mg 98% ¥290.00元 >10 - - -
源叶(MedMol) S80189-25mg 98% ¥520.00元 >10 - - -
源叶(MedMol) S80189-50mg 98% ¥700.00元 >10 - - -
源叶(MedMol) S80189-100mg 98% ¥970.00元 >10 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Faropenem sodium是具有口服活性的β-内酰胺抗生素,用于研究治疗肺结核和社区获得性肺炎的试验中。
产品描述: Faropenem sodium是具有口服活性的β-内酰胺抗生素,用于研究治疗肺结核和社区获得性肺炎的试验中。
靶点: Antibacterial;Antibiotic
细胞实验: Cell lines: RAW macrophages Concentrations: 7, 28, or 56 μg/ml Incubation Time: -- Method: RAW macrophages were grown in Dulbecco modified Eagle medium containing l-glutamine and sodium pyruvate (PAA Laboratories) supplemented with 10% fetal bovine serum. About 2.5 × 104 cells were seeded into each well of a 48-well plate and were infected with green fluorescent protein (GFP)-expressing M. tuberculosis (MTB_NDT1) at a multiplicity of infection (MOI) of 10:1 for 4 h. After infection, the monolayers were washed three times with fresh medium to remove nonadherent bacteria and then exposed to fresh medium with or without isoniazid (0.75 μg/ml), faropenem (7, 28, or 56 μg/ml), or meropenem (5, 25, or 50 μg/ml) plus clavulanate (2.5 μg/ml). Medium (containing antibiotics) was changed every 24 h. At various time points, macrophages were washed once with 1× PBS and then lysed using 0.5% Triton X-100. The macrophage lysates were diluted in PBS containing 0.05% Tween 80, serial dilutions were plated on 7H10 agar, a
动物实验: Animal Models: Adult female C57BL/6J mice Dosages: 500 mg/kg Administration: oral
参考文献: 1. Dhar N, et al. Antimicrob Agents Chemother. 2015, 59(2):1308-19.
溶解性: Soluble  in  DMSO、H2O
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.254 ml 16.271 ml 32.542 ml
5 mM 0.651 ml 3.254 ml 6.508 ml
10 mM 0.325 ml 1.627 ml 3.254 ml
50 mM 0.065 ml 0.325 ml 0.651 ml
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参考文献

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