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• 产品描述： Satraplatin is an orally available antineoplastic platinum(IV) complex.Satraplatin has a favorable toxicity profile and appears to have clinical activity against a variety of malignancies.

• 靶点： DNA Alkylation;DNA Alkylator/Crosslinker;DNAAlkylator/Crosslinker;DNAAlkylation

• 细胞实验： CDDP-resistant (KB-R) cells and parental cells (KB) pair were used. Viability was assessed using the MTT and clonogenic assay. Real-time polymerase chain reaction (PCR), glutathione (GSH) assay, and flow cytometric analysis were used for further assessment

• 参考文献：
  1. Yamano Y , Shiiba M , Negoro K , et al. Antitumor activity of satraplatin in cisplatin-resistant oral squamous cell carcinoma cells[J]. Head & Neck, 2010, 33(3):309-317. 2. Bhargava A , Vaishampayan U N . Satraplatin: leading the new generation of oral platinum agents[J]. Expert Opinion on Investigational Drugs, 2009, 18(11):1787-1797.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20°C

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	1.999 ml	9.994 ml	19.989 ml
  5 mM	0.4 ml	1.999 ml	3.998 ml
  10 mM	0.2 ml	0.999 ml	1.999 ml
  50 mM	0.04 ml	0.2 ml	0.4 ml

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *