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产品描述： UNC1215 is a potent and selective inhibitor for the methyllysine (Kme) reading domain function of L3MBTL3 with a Kd value of 120 nM and an IC50 of 40 nM. UNC1215 has the potential to treat malignant brain tumor. |
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靶点：
IC50: 40 nM (L3MBTL3). Kd: 120 nM (L3MBTL3).;Apoptosis;EpigeneticReaderDomain;HistoneMethyltransferase |
参考文献：
1. James LI, Barsyte-Lovejoy D, Zhong N, et al. Discovery of a chemical probe for the L3MBTL3 methyllysine reader domain. Nat Chem Biol. 2013 Mar;9(3):184-91. doi: 10.1038/nchembio.1157. |
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溶解性：
DMSO : ≥ 270 mg/mL (509.70 mM) |
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保存条件：
2-8℃ |
配置溶液浓度参考：
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1mg |
5mg |
10mg |
| 1 mM |
1.888 ml |
9.439 ml |
18.878 ml |
| 5 mM |
0.378 ml |
1.888 ml |
3.776 ml |
| 10 mM |
0.189 ml |
0.944 ml |
1.888 ml |
| 50 mM |
0.038 ml |
0.189 ml |
0.378 ml |
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| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
北京