CALCIPOTRIOL MONOHYDRATE

    
99%

CALCIPOTRIOL MONOHYDRATE

源叶(MedMol)
S80375 一键复制产品信息
147657-22-5
C27H40O3.H2O
430.62
钙泊三醇一水合物;卡泊三醇单水合物;卡泊三醇一水合物;CALCIPOTRIOL MONOHYDRATE;(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4S)-4-cyclopropyl-4-hydroxy-1-methyl-2-buten-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-
货号 规格 价格 上海 北京 武汉 南京 购买数量
S80375-10mg 99% ¥670.00 2 - - -
S80375-50mg 99% ¥2100.00 货期:2-3天 - - -
S80375-100mg 99% ¥3750.00 货期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.

产品描述: Calcipotriol monohydrate is a synthetic VitD3 analogue with a high affinity for the vitamin D receptor.
靶点: vitamin D receptor
体内研究: One out of the 32 animals in each of the groups has died, except for the Diclofenac plus DFMO plus Calcipotriol group, where all animals survived. Survival is equally distributed between the groups. The weight gain is significantly smaller in the groups treated with Diclofenac plus Calcipotriol (p=0.018) and Diclofenac plus DFMO plus Calcipotriol (p=0.002) compare with placebo (linear regression model)
参考文献: 1. Al-Jaderi Z, et al. Effects of vitamin D3, calcipotriol and FTY720 on the expression of surface molecules and cytolytic activities of human natural killer cells and dendritic cells. Toxins (Basel). 2013 Oct 28;5(11):1932-47. 2. Sakabe JI, et al. Calcipotriol Increases hCAP18 mRNA Expression but Inhibits Extracellular LL37 Peptide Production in IL-17/IL-22-stimulated Normal Human Epidermal Keratinocytes. Acta Derm Venereol. 2014 Sep;94(5):512-6. 3. Pommergaard HC, et al. Combination chemoprevention with diclofenac, calcipotriol and difluoromethylornithine inhibits development of non-melanoma skin cancer in mice. Anticancer Res. 2013 Aug;33(8):3033-9.
溶解性: Soluble  in  DMSO、Ethanol
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.322 ml 11.611 ml 23.222 ml
5 mM 0.464 ml 2.322 ml 4.644 ml
10 mM 0.232 ml 1.161 ml 2.322 ml
50 mM 0.046 ml 0.232 ml 0.464 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

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