产品描述: | Clemastine (HS-592) fumarate is a selective histamine H1 receptor antagonist. Clemastine fumarate is an antihistamine mainly used for relieving symptoms of allergic reactions primarily by competing with histamine to bind H1 receptors. Anti-inflammatory effects |
靶点: |
H1 Receptor;Autophagy;HistamineReceptor |
参考文献: |
1. Seifert, R., et al., Histamine increases cytosolic Ca2+ in dibutyryl-cAMP-differentiated HL-60 cells via H1 receptors and is an incomplete secretagogue. Mol Pharmacol, 1992. 42(2): p. 227-34. 2. Clemastine. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; January 16, 2017. |
溶解性: |
DMSO : 14.29 mg/mL (31.07 mM; Need ultrasonic) H2O : 0.67 mg/mL (1.46 mM; Need ultrasonic) |
保存条件: |
2-8℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
2.174 ml |
10.871 ml |
21.741 ml |
5 mM |
0.435 ml |
2.174 ml |
4.348 ml |
10 mM |
0.217 ml |
1.087 ml |
2.174 ml |
50 mM |
0.043 ml |
0.217 ml |
0.435 ml |
|
注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |