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Travoprost 98%

Travoprost

源叶(MedMol)
S80408
157283-68-6
C26H35F3O6
500.548
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S80408-5mg 98% ¥850.00元 2 - - -
源叶(MedMol) S80408-10mg 98% ¥1290.00元 2 - - -
源叶(MedMol) S80408-50mg 98% ¥2850.00元 >10 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Travoprost (Fluprostenol isopropyl ester), an isopropyl ester prodrug, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension
产品描述: Travoprost (Fluprostenol isopropyl ester), an isopropyl ester prodrug, is a high affinity, selective FP prostaglandin full receptor agonist. Travoprost has the ocular hypotensive efficacy and has the potential for glaucoma and ocular hypertension
靶点: FP;ProstaglandinReceptor
体内研究:
Travoprost produces a lower incidence of ocular irritation than PGF20 isopropyl ester at a dose of 1 μg in the New Zealand albino (NZA) rabbit. Topical ocular application of Travoprost produces a marked miotic effect in cats following doses of 0.01, 0.03 and 0.1 μg. In the ocular hypertensive monkey, b.i.d. application of 0.1 and 0.3 μg of travoprost afforded peak reduction in intraocular pressure (IOP) of 22.7% and 28.6%, respectively. Topical application of travoprost was well tolerated in rabbits, cats and monkeys, causing no ocular irritation or discomfort at doses up to 1 μg
参考文献:
1. M R Hellberg, et al. Preclinical efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist. J Ocul Pharmacol Ther. 2001 Oct;17(5):421-32.
溶解性: Ethanol  :  60  mg/mL  (119.87  mM;  Need  ultrasonic)    DMSO  :  ≥  41.67  mg/mL  (83.25  mM)
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 1.998 ml 9.989 ml 19.978 ml
5 mM 0.4 ml 1.998 ml 3.996 ml
10 mM 0.2 ml 0.999 ml 1.998 ml
50 mM 0.04 ml 0.2 ml 0.4 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

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