| 产品描述： | Cinoxacin (Compound 64716), a synthetic antimicrobial related to the quinolone class of orally active antibacterial agent. Cinoxacin has antibacterial activity against many gram-negative aerobic bacteria and inhibits bacterial DNA synthesis. Cinoxacin can be used for the research of urinary tract infections and bacterial prostatitis |
| 靶点： |
Quinolone;Topoisomerase;Antibacterial;Antibiotic |
| 体内研究： |
Cinoxacin (Oral administration, 1.7 g/kg, treated at 1 and 5 h postinfection) is effective in experimental bacterial infections in mice, with ED50 values ranging from 8.1 to 58.6 mg/kg |
| 参考文献： |
1. Scavone JM, et al. Cinoxacin: mechanism of action, spectrum of activity, pharmacokinetics, adverse reactions, and therapeutic indications. Pharmacotherapy. 1982 Sep-Oct;2(5):266-72. 2. W E Wick, et al. Compound 64716, a new synthetic antibacterial agent. Antimicrob Agents Chemother. 1973 Oct;4(4):415-20. |
| 溶解性： |
DMSO : 8.33 mg/mL (31.77 mM; Need ultrasonic) |
| 保存条件： |
RT |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
3.814 ml |
19.068 ml |
38.136 ml |
| 5 mM |
0.763 ml |
3.814 ml |
7.627 ml |
| 10 mM |
0.381 ml |
1.907 ml |
3.814 ml |
| 50 mM |
0.076 ml |
0.381 ml |
0.763 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京