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产品描述： Buspirone hydrochloride is a 5-HT1A receptor agonist. Buspirone hydrochloride can be used for anxiety and depression research |
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靶点：
5-HT Receptor;Reactive Oxygen Species;DopamineReceptor;5-HTReceptor |
体内研究：
Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) reduces anxiety/depression behaviors. Buspirone hydrochloride (1-5 mg/kg; i.p. and i.g.; for 5 days; C57BL/6N mice) restores IS-shifted β-diversity in the gut microbiota. |
参考文献：
1. Salimi A, et, al. Analysis of Toxicity Effects of Buspirone, Cetirizine and Olanzapine on Human Blood Lymphocytes: in Vitro Model. Curr Clin Pharmacol. 2018;13(2):120-127. 2. Kim JK, et, al. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Sci Rep. 2021 Mar 17;11(1):6094. |
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溶解性：
H2O : ≥ 100 mg/mL (236.99 mM) DMSO : 50 mg/mL (118.49 mM; Need ultrasonic) |
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保存条件：
-20℃ |
配置溶液浓度参考：
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1mg |
5mg |
10mg |
| 1 mM |
2.37 ml |
11.849 ml |
23.699 ml |
| 5 mM |
0.474 ml |
2.37 ml |
4.74 ml |
| 10 mM |
0.237 ml |
1.185 ml |
2.37 ml |
| 50 mM |
0.047 ml |
0.237 ml |
0.474 ml |
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| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
北京