S80684 |
Procarbazine HCl |
源叶(MedMol) | 95% |
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- 产品描述: Procarbazine Hydrochloride is an orally active alkylating agent, with anticancer activity. Procarbazine Hydrochloride can be used in Hodgkin's disease research
- 靶点: DNA Alkylator/Crosslinker;DNAAlkylator/Crosslinker; DNA/RNASynthesis
- 体内研究:
Procarbazine (Intraperitoneal injection; 50 and 150 mg/kg; once daily; 5 d) induces micronuclei in hematopoietic cells, but not increases the lacZ mutant frequency (MF) in bone marrow
- 参考文献:
1. J M Erikson, et al. Cytotoxicity and DNA damage caused by the azoxy metabolites of procarbazine in L1210 tumor cells. Cancer Res. 1989 Jan 1;49(1):127-33. 2. T Suzuki, et al. Procarbazine genotoxicity in the MutaMouse; strong clastogenicity and organ-specific induction of lacZ mutations. Mutat Res. 1999 Aug 18;444(2):269-81.
- 溶解性: H2O : 100 mg/mL (387.96 mM; Need ultrasonic) DMSO : 16.67 mg/mL (64.67 mM; Need ultrasonic)
- 保存条件: 2-8℃
- 配置溶液浓度参考:
1mg 5mg 10mg 1 mM 3.88 ml 19.398 ml 38.796 ml 5 mM 0.776 ml 3.88 ml 7.759 ml 10 mM 0.388 ml 1.94 ml 3.88 ml 50 mM 0.078 ml 0.388 ml 0.776 ml
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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:
质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)