产品描述: | VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. VU 0357121 is inactive or very weakly antagonizing at other mGlu receptor subtypes |
靶点: |
mGlu5 Receptor:33 nM (EC50);GluR |
参考文献: |
1. Hammond. Alexis S, et al. Discovery of a Novel Chemical Class of mGlu5 Allosteric Ligands with Distinct Modes of Pharmacology. ACS Chemical Neuroscience (2010), 1(10), 702-716. |
溶解性: |
DMSO : ≥ 50 mg/mL (163.76 mM) |
保存条件: |
-20℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
3.275 ml |
16.376 ml |
32.753 ml |
5 mM |
0.655 ml |
3.275 ml |
6.551 ml |
10 mM |
0.328 ml |
1.638 ml |
3.275 ml |
50 mM |
0.066 ml |
0.328 ml |
0.655 ml |
|
注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |