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• 产品描述： Carmofur is a highly potent acid ceramidase inhibitor, used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.

• 靶点： DNA/RNA Synthesis;Nucleoside Antimetabolite/Analog;SARS-CoV;Virus Protease;NucleosideAntimetabolite/Analog;VirusProtease;SARS-CoV;DNA/RNASynthesis

• 参考文献：
  1.Bowden G D, Land K M, O'Connor R M, et al. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth[J]. International Journal for Parasitology: Drugs and Drug Resistance. 2018 Apr；8(1): 137-144. 2.Akiba T, et al. Acta Neuropathol,1996, 92(1), 8-13. 3.Sato S, et al. Gan To Kagaku Ryoho,1999, 26(11), 1613-1616. 4.Kuzuhara S, et al. J Neurol,1987, 234(6), 365-370.

• 溶解性： H2O:<1  mg/mL    Ethanol:10  mg/mL  (38.87  mM)    DMSO:49  mg/mL  (190.5  mM)

• 保存条件： 2-8℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	3.887 ml	19.436 ml	38.871 ml
  5 mM	0.777 ml	3.887 ml	7.774 ml
  10 mM	0.389 ml	1.944 ml	3.887 ml
  50 mM	0.078 ml	0.389 ml	0.777 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 1. [4.4] Qu Minmin et al."Assessing genotoxic effects of chemotherapy agents by a robust in vitro assay based on mass spectrometric quantification of γ-H2AX in HepG2 cells."Frontiers in Pharmacology.2024 Jun;15:

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *