| 产品描述： | Pergolide mesylate (Pergolide methanesulfonate), an Ergoline derivative, is a potent and orally active dopamine D1 and D2 receptors agonist. Pergolide mesylate can be used for Parkinson's disease and hyperprolactinaemia research |
| 靶点： |
D2 Receptor;D1 Receptor;DopamineReceptor;5-HTReceptor;AdrenergicReceptor |
| 体内研究： |
Pergolide (0.3 mg/kg; intraperitoneal injection; daily; 11 days) treatment reduces the number of working/reference memory errors a 6-OHDA-induced rat model of Parkinson's disease. Pergolide facilitates spatial memory and improves brain oxidative balance |
| 参考文献： |
1. S Franks, et al. Effectiveness of pergolide mesylate in long term treatment of hyperprolactinaemia. Br Med J (Clin Res Ed). 1983 Apr 9;286(6372):1177-9. 2. Daniela Uberti, et al. Pergolide protects SH-SY5Y cells against neurodegeneration induced by H(2)O(2). Eur J Pharmacol. 2002 Jan 2;434(1-2):17-20. 3. Alin Ciobica, et al. The effects of pergolide on memory and oxidative stress in a rat model of Parkinson's disease. J Physiol Biochem. 2012 Mar;68(1):59-69. |
| 溶解性： |
DMSO : ≥ 25 mg/mL (60.89 mM) |
| 保存条件： |
-20℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.435 ml |
12.177 ml |
24.355 ml |
| 5 mM |
0.487 ml |
2.435 ml |
4.871 ml |
| 10 mM |
0.244 ml |
1.218 ml |
2.435 ml |
| 50 mM |
0.049 ml |
0.244 ml |
0.487 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京