| 产品描述： | Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome. |
| 靶点： |
Oxazolidinone;MAO; Antibacterial; Antibiotic |
| 体内研究： |
For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema |
| 参考文献： |
1. Choi S, et al. Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-resistant and Penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Jun 19. |
| 溶解性： |
DMSO : 10 mg/mL (27.00 mM; Need ultrasonic) |
| 保存条件： |
2-8℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
2.7 ml |
13.501 ml |
27.002 ml |
| 5 mM |
0.54 ml |
2.7 ml |
5.4 ml |
| 10 mM |
0.27 ml |
1.35 ml |
2.7 ml |
| 50 mM |
0.054 ml |
0.27 ml |
0.54 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京