| 产品描述： | DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities. |
| 靶点： |
gp120BaL/sCD4-CCR5:55 pM (IC50, in Cf2Th/synR5 cells);gp120CMCM235/sCD4-CCR5:0.32 nM (IC50, in Cf2Th/synR5 cells);HIVProtease; CCR |
| 参考文献： |
1. Pollicita M, et al. Profound anti-HIV-1 activity of DAPTA in monocytes/macrophages and inhibition of CCR5-mediated apoptosis in neuronal cells. Antivir Chem Chemother. 2007;18(5):285-95. 2. Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. 2005 Aug;67(2):83-92. |
| 溶解性： |
H2O : 50 mg/mL (58.35 mM; Need ultrasonic) |
| 保存条件： |
-20℃ |
| 配置溶液浓度参考： |
|
1mg |
5mg |
10mg |
| 1 mM |
1.167 ml |
5.835 ml |
11.67 ml |
| 5 mM |
0.233 ml |
1.167 ml |
2.334 ml |
| 10 mM |
0.117 ml |
0.584 ml |
1.167 ml |
| 50 mM |
0.023 ml |
0.117 ml |
0.233 ml |
|
| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
危险品化学品经营许可证（不带存储）
营业执照(三证合一)
北京