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• 产品描述： Cefoselis is a widely used beta-lactam antibiotic.

• 靶点： Antibacterial;Antibiotic;Antibacterial; Antibiotic

• 体内研究：
  Cefoselis elicits a massive elevation of extracellular glutamate concentration in normal rats. Cefoselis (50 mg/animal)-induced convulsions are prevented by pretreatment with 5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801), diazepam and phenobarbital (ED(50) values (mg/kg) of 0.78, 1.59 and 33.0, respectively), but not by carbamazepine or phenytoin.

• 参考文献：
  1. Yamazaki S, et al. Pharmacol Biochem Behav, 2002, 74(1), 53-59. 2. Ohtaki K, et al. J Neural Transm, 2004, 111(12), 1523-1535. 3. Yamada K, et al. J Infect Chemother, 2012, 18(4), 472-478. 4. Sugimoto M, et al. Br J Pharmacol, 2002, 135(2), 427-432. 5. Giamarellos-Bourboulis EJ, et al. Diagn Microbiol Infect Dis, 2000, 36(3), 185-191.

• 溶解性： Soluble  in  DMSO

• 保存条件： -20℃;充氩

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	1.611 ml	8.056 ml	16.113 ml
  5 mM	0.322 ml	1.611 ml	3.223 ml
  10 mM	0.161 ml	0.806 ml	1.611 ml
  50 mM	0.032 ml	0.161 ml	0.322 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 1. [IF=3.681] Dong Wei-chong et al."A Direct Injection Technique to Improve Biosafety to Analyze Levetiracetam Concentrations in Human Serum and Its Application in Therapeutic Drug Monitoring."Ther Drug Monit. 2021 Apr;43(2):292-297

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *