Sevelamer hydrochloride 98%

Sevelamer hydrochloride

源叶(MedMol)
S81359
152751-57-0
C6H12ClNO
149.619
盐酸司维拉姆;2-丙烯-1-胺与环氧氯丙烷的聚合物盐酸盐;司维拉姆盐酸盐;SEVELAMER HCL;Sevelemar;Sevelamer Hydrochloride;2-Propen-1-amine polymer with (chloromethyl)oxirane hydrochloride;(ChloroMethyl)oxirane polyMer with 2-Propen-1-aMi
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S81359-100mg 98% ¥600.00元 预计交期:2-3天 - - -
源叶(MedMol) S81359-500mg 98% ¥1800.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin
产品描述: Sevelamer hydrochloride is an orally active and phosphate binding agent used for research of hyperphosphatemia with chronic kidney disease. Sevelamer hydrochloride consists of polyallylamine that is crosslinked with epichlorohydrin
靶点: FXR;Autophagy;FXR; Autophagy
体内研究: Sevelamer hydrochloride (1% mixed in diet; p.o.; once daily for 5 weeks) reduces Npt2b-deficient mice serum phosphate levels, but fails to reduce the level in uremic WT mice.Sevelamer hydrochloride leads to a significant decrease in osteoclast number in uremic WT mice with a trend toward further decrease in Npt2b-/- mice.Sevelamer hydrochloride leads to a significant increase in Npt2b protein expression
参考文献: 1. Sevelamer, From Wikipedia 2. Bennis Y, et al. The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial. Toxins (Basel). 2019 May 17;11(5):279. 3. Susan C Schiavi, et al. Npt2b deletion attenuates hyperphosphatemia associated with CKD. J Am Soc Nephrol. 2012 Oct;23(10):1691-700.
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 6.684 ml 33.418 ml 66.836 ml
5 mM 1.337 ml 6.684 ml 13.367 ml
10 mM 0.668 ml 3.342 ml 6.684 ml
50 mM 0.134 ml 0.668 ml 1.337 ml
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参考文献

质检证书(COA)

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摩尔浓度计算器

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