欢迎光临源叶生物,登录 | 注册 |
当前位置: 首页 > 小分子抑制剂 > GPCR/GProtein > 5-Iodotubercidin

浏览历史

S81442

5-Iodotubercidin

源叶(MedMol) 98%
  • 英文名:
  • 5-Iodotubercidin
  • 别名:
  • 5-碘代杀结核菌素;4-Amino-5-iodo-7-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine;5-Iodotubercidin; 5-IODOTUBERCIDIN; 5-Iodotubericidin;
  • CAS号:
  • 24386-93-4
  • 分子式:
  • C11H13IN4O4
  • 分子量:
  • 392.15
  • 核磁/质谱:
品牌货号产品规格价格(RMB) 库存(上海) 北京 武汉 南京 数量计量单位 加入购物车...
源叶(MedMol) S81442-2mg 98% ¥400.00元 >10 - - - EA 加入购物车
源叶(MedMol) S81442-5mg 98% ¥600.00元 >10 - - - EA 加入购物车
源叶(MedMol) S81442-25mg 98% ¥2000.00元 >10 - - - EA 加入购物车
大包装询价

提交您的电话号码并同意《个人信息授权与保护申明》,到货后将短信提示。
提交

产品介绍

参考文献

质检证书(COA)

摩尔浓度计算器

相关产品

  • 提示:详情请下载说明书。
  • 产品描述: 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin
  • 靶点: IC50: 26 nM (adenosine kinase);AdenosineReceptor
  • 体内研究:
    5-Iodotubercidin (1 mL/kg, i.p.) is in agreement with activity observed against bicuculline-induced seizures following local administration of the AKI into the prepiriform cortex
  • 参考文献:
    1. Massillon D, et al. Identification of the glycogenic compound 5-iodotubercidin as a general protein kinase inhibitor. Biochem J. 1994 Apr 1;299 (Pt 1):123-8. 2. Ugarkar BG, et al. Adenosine kinase inhibitors. 1. Synthesis, enzyme inhibition, and antiseizure activity of 5-iodotubercidin analogues. J Med Chem. 2000 Jul 27;43(15):2883-93. 3. García-Villafranca J, et al. Effects of 5-iodotubercidin on hepatic fatty acid metabolism mediated by the inhibition of acetyl-CoA carboxylase. Biochem Pharmacol. 2002 Jun 1;63(11):1997-2000. 4. De Antoni A, et al. A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B. J Cell Biol. 2012 Oct 15;199(2):269-84. 5. Acharya MM, et al. Adenosine Kinase Inhibition Protects against Cranial Radiation-Induced Cognitive Dysfunction. Front Mol Neurosci. 2016 Jun 3;9:42.
  • 溶解性: DMSO  :  25  mg/mL  (63.75  mM;  Need  ultrasonic)
  • 保存条件: 2-8℃
  • 配置溶液浓度参考:
    1mg 5mg 10mg
    1 mM 2.55 ml 12.75 ml 25.5 ml
    5 mM 0.51 ml 2.55 ml 5.1 ml
    10 mM 0.255 ml 1.275 ml 2.55 ml
    50 mM 0.051 ml 0.255 ml 0.51 ml
  • 注意:部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。
输入产品批号:

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系,公式为:


质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)


  • =
    *
    *


源叶所有产品仅用作科学研究,销售产品行为均适用于我司网上所列通用销售条款。