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• 产品描述： (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.

• 靶点： Human Endogenous Metabolite;EstrogenReceptor/ERR; Estrogen/progestogenReceptor; EndogenousMetabolite

• 体内研究：
  (-)-(S)-Equol inhibits the tumor growth by 43.2% and 28.4% compared to the control on day 33, suggesting that the compound is not overtly toxic

• 参考文献：
  1. Setchell KD, et al. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. Am J Clin Nutr. 2005 May;81(5):1072-9. 2. Lu Z, et al. S-equol, a Secondary Metabolite of Natural Anticancer Isoflavone Daidzein, Inhibits Prostate Cancer Growth In Vitro and In Vivo, Though Activating the Akt/FOXO3a Pathway. Curr Cancer Drug Targets. 2016;16(5):455-65. 3. Horiuchi H, et al. S-equol nantioselectively activates cAMP-protein kinase A signaling and reduces alloxan-induced cell death in INS-1 pancreatic β-cells. J Nutr Sci Vitaminol (Tokyo). 2014;60(4):291-6.

• 溶解性： DMSO  :  100  mg/mL  (412.76  mM;  Need  ultrasonic  and  warming)

• 保存条件： -20℃

• 配置溶液浓度参考：
  

  	1mg	5mg	10mg
  1 mM	4.128 ml	20.638 ml	41.276 ml
  5 mM	0.826 ml	4.128 ml	8.255 ml
  10 mM	0.413 ml	2.064 ml	4.128 ml
  50 mM	0.083 ml	0.413 ml	0.826 ml

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 2. [5.1] Xiaoying Wang et al."Preparation of Lactobacillus rhamnosus ATCC 7469 microencapsulated-lactulose synbiotic and its effect on equol production."Food & Function.2024 Aug;:

• 1. [IF=5.396] Cong Lu et al."S-equol, a metabolite of dietary soy isoflavones, alleviates lipopolysaccharide-induced depressive-like behavior in mice by inhibiting neuroinflammation and enhancing synaptic plasticity."Food Funct. 2021 Jul;12(13):5770-5778

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *