ZCL278

    
95%

ZCL278

源叶(MedMol)
S81497 一键复制产品信息
587841-73-4
C21H19BrClN5O4S2
货号 规格 价格 上海 北京 武汉 南京 购买数量
S81497-2mg 95% ¥272.00 5 - - -
S81497-5mg 95% ¥340.00 6 - - -
S81497-10mg 95% ¥586.50 4 - - -
S81497-25mg 95% ¥1122.00 6 - - -
S81497-50mg 95% ¥1955.00 5 - - -
S81497-100mg 95% ¥2975.00 货期:2-3天 - - -
S81497-200mg 95% ¥5525.00 货期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

ZCL278 is a selective Cdc42 modulator that directly binds to Cdc42 and inhibits its functions with Kd of 11.4 μM for Cdc42-ZCL278 affinity in surface plasmon resonance (SPR) experiment.

产品描述: ZCL278 is a selective Cdc42 modulator that directly binds to Cdc42 and inhibits its functions with Kd of 11.4 μM for Cdc42-ZCL278 affinity in surface plasmon resonance (SPR) experiment.
靶点: Kd: 11.4 μM (Cdc42);CDK; Ras
体内研究: ZCL278 reduces the JUNV RNA load in the spleen more than 33-fold, with JUNV RNA being undetectable in 5 out of 8 mice. These results are similar to those seen in Gabapentin-treated mice, demonstrating that ZCL278 can abrogate JUNV replication
参考文献: 1. Friesland A, et al. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1261-6. 2. Chou YY, et al. Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor. J Virol. 2016 Apr 14;90(9):4494-510.
溶解性: DMSO  :  50  mg/mL  (85.49  mM;  Need  ultrasonic)
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 0 ml 0 ml 0 ml
5 mM 0 ml 0 ml 0 ml
10 mM 0 ml 0 ml 0 ml
50 mM 0 ml 0 ml 0 ml
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参考文献

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摩尔浓度计算器

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