Camostat Mesilate

    
98%

Camostat Mesilate

源叶(MedMol)
S81499 一键复制产品信息
59721-29-8
C21H26N4O8S
494.52
甲磺酸卡莫司他;2-(二甲基氨基)-2-氧代乙基 4-(4-胍基苯甲酰氧基)苯乙酸酯甲磺酸盐;4-((4-((AmInoimInomethyl)AmIno)Benzoyl)Oxy)-Benzeneaceticaci2-(Dimethylam;Ino)-2-Oxoethylester,Monomethanesulfonate;n,n-Dimethylcarbamoylmethyl4-(4-guani
货号 规格 价格 上海 北京 武汉 南京 购买数量
S81499-10mg 98% ¥150.00 >10 - - -
S81499-50mg 98% ¥500.00 >10 - - -
S81499-250mg 98% ¥1400.00 >10 - - -
S81499-1g 98% ¥3800.00 >10 - - -
产品介绍 参考文献(1篇) 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase

产品描述: Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase
靶点: Ser/Thr Protease;SARS-CoV;Serine/threoninkinase; SARS-CoV; SodiumChannel
体内研究: Camostat mesilate (30 mg/kg; p.o.; twice a day for 9 days) blocks the spread and pathogenesis of SARS-CoV in a pathogenic mouse model
参考文献: 1. Gibo J, et al. Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. Lab Invest. 2005;85(1):75‐89. 2. Uno Y. Camostat mesilate therapy for COVID-19 [published online ahead of print, 2020 Apr 29]. Intern Emerg Med. 2020;1‐2. 3. Coote K, et al. Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. J Pharmacol Exp Ther. 2009;329(2):764‐774. 4. Zhou Y, Vedantham P, Lu K, et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015;116:76‐84.
溶解性: DMSO  :  125  mg/mL  (252.77  mM;  Need  ultrasonic)    H2O  :  ≥  50  mg/mL  (101.11  mM)
保存条件: RT
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.022 ml 10.111 ml 20.222 ml
5 mM 0.404 ml 2.022 ml 4.044 ml
10 mM 0.202 ml 1.011 ml 2.022 ml
50 mM 0.04 ml 0.202 ml 0.404 ml
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质检证书(COA)

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摩尔浓度计算器

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