产品描述: | IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor associated kinase 4 (IRAK-4) with IC50 of 160 nM. |
靶点: |
IC50: 160 nM (IRAK-4);IRAK |
体外研究: |
IRAK inhibitor 6 significantly improves potency against IRAK-4. Potency effects additive, IRAK inhibitor 6 is the most active compound among these compound tested |
参考文献: |
1. Buckley G, et al. IRAK-4 inhibitors. Part 1: a series of amides. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3211-4. |
溶解性: |
soluble in DMSO |
保存条件: |
-20℃ |
配置溶液浓度参考: |
|
1mg |
5mg |
10mg |
1 mM |
2.522 ml |
12.612 ml |
25.223 ml |
5 mM |
0.504 ml |
2.522 ml |
5.045 ml |
10 mM |
0.252 ml |
1.261 ml |
2.522 ml |
50 mM |
0.05 ml |
0.252 ml |
0.504 ml |
|
注意: |
部分产品我司仅能提供部分信息,我司不保证所提供信息的权威性,仅供客户参考交流研究之用。 |