品牌	货号	产品规格	价格(RMB)	库存（上海）	北京	武汉	南京	购买数量
源叶(MedMol)	S82118-10mg	99%	￥1080.00元	4	-	-	-
源叶(MedMol)	S82118-50mg	99%	￥3200.00元	3	-	-	-

产品介绍

Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection

产品描述：

靶点：

Bacterial;Antibiotic;DNA/RNA Synthesis;Others; Antibiotic

体内研究：

Azaserine (5 mg/kg; i.p. once or twice a week for 6 months) induces tumor in rats

参考文献：

1. Longnecker DS, Curphey TJ. Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res. 1975 Aug;35(8):2249-58. 2. Shigemichi GUNJI, et al. Screening of Antifungal Antibiotics According to Activities Inducing Morphological Abnormalities. Agric. Biol Chem., 47 (9), 2061-2069, 1983. 3. Williams MV, Tritz GJ. Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal. J Antimicrob Chemother. 1977 Jan;3(1):65-77. 4. Catane R, et al. Azaserine, DON, and azotomycin: three diazo analogs of L-glutamine with clinical antitumor activity. Cancer Treat Rep. 1979 Jun;63(6):1033-8. 5. Lyons SD, et al. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265(19):11377-81.

溶解性：

H2O : 50 mg/mL (288.80 mM; Need ultrasonic)

保存条件：

2-8℃

配置溶液浓度参考：

	1mg	5mg	10mg
1 mM	5.776 ml	28.881 ml	57.761 ml
5 mM	1.155 ml	5.776 ml	11.552 ml
10 mM	0.578 ml	2.888 ml	5.776 ml
50 mM	0.116 ml	0.578 ml	1.155 ml

注意：

部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(1篇)

1. [IF=3.682] Wenhui Xu et al."Effect of Dihydroartemisinin on Plasmodium NADH-Dependent Glutamate Synthase: The Implication in Malaria Management."Am J Chinese Med. 2019 Sep;47(06):1325-1343

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摩尔浓度计算器

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

质量

浓度

体积

分子摩尔量

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AZASERINE