| 货号 | 产品规格 | 价格(RMB) | 库存（上海） | 北京 | 武汉 | 南京 | 购买数量 |
|---|---|---|---|---|---|---|---|
| S83235-5mg | 98% | ￥400.00元 |
预计交期：咨询 | - | - | - |
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| S83235-10mg | 98% | ￥550.00元 |
预计交期：咨询 | - | - | - |
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| S83235-50mg | 98% | ￥1200.00元 |
预计交期：咨询 | - | - | - |
|
| S83235-100mg | 98% | ￥1800.00元 |
预计交期：咨询 | - | - | - |
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Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents.
| 产品描述： | Miriplatin (SM-11355) is a chemotherapy agent which belongs to the class of alkylating agents. | ||||||||||||||||||||
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| 靶点： | DNA Alkylator/Crosslinker;DNAAlkylator/Crosslinker | ||||||||||||||||||||
| 体外研究： | Miriplatin (SM-11355) suspended in LPD (miriplatin/LPD, 100 μg/mL) inhibits the growth of AH109A cells, forms platinum-DNA adducts, and induces apoptosis | ||||||||||||||||||||
| 体内研究： | Miriplatin (SM-11355) (0.02-0.4 mg/20 μL) in lipiodol reduces tumor growth rates in a dose dependent manner in rats bearing AH109A tumor cells. Miriplatin/LPD (400 μg/head) significantly reduces the growth of tumor in rats bearing AH109A cells | ||||||||||||||||||||
| 参考文献： | 1. Kishimoto S, et al. Antitumor effects of a novel lipophilic platinum complex (SM-11355) against a slowly-growing rat hepatic tumor after intra-hepatic arterial administration. Biol Pharm Bull. 2000 Mar;23(3):344-8. 2. Hanada M, et al. Intra-hepatic arterial administration with miriplatin suspended in an oily lymphographic agent inhibits the growth of tumors implanted in rat livers by inducing platinum-DNA adducts to form and massive apoptosis. Cancer Chemother Pharmacol. 2009 Aug;64(3):473-83. | ||||||||||||||||||||
| 溶解性： | 10 mM in DMSO | ||||||||||||||||||||
| 保存条件： | -20℃ | ||||||||||||||||||||
| 配置溶液浓度参考： |
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| 注意： | 部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
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