TAPI-2 (TNF Protease Inhibitor 2) 95%

N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alanina

源叶(MedMol)
S84109
187034-31-7
C21H41N5O7
475.58
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S84109-1mg 95% ¥1500.00元 预计交期:2-3天 - - -
源叶(MedMol) S84109-5mg 95% ¥6000.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP. TAPI-2 blocks the entry of infectious SARS-CoV
产品描述: TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP. TAPI-2 blocks the entry of infectious SARS-CoV
靶点: MMP:20 μM (IC50);MMP
参考文献: 1. Kruse MN, et al. Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors. Biochem J. 2004 Mar 1;378(Pt 2):383-9. 2. Shiori Haga, et al. TACE Antagonists Blocking ACE2 Shedding Caused by the Spike Protein of SARS-CoV Are Candidate Antiviral Compounds. Antiviral Res. 2010 Mar;85(3):551-5. 3. Wang R, et al. A Disintegrin and Metalloproteinase Domain 17 Regulates Colorectal Cancer Stem Cells and Chemosensitivity Via Notch1 Signaling. Stem Cells Transl Med. 2016 Mar;5(3):331-8.
溶解性: Soluble  in  DMSO、H2O
保存条件: 2-8℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 2.103 ml 10.513 ml 21.027 ml
5 mM 0.421 ml 2.103 ml 4.205 ml
10 mM 0.21 ml 1.051 ml 2.103 ml
50 mM 0.042 ml 0.21 ml 0.421 ml
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参考文献

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摩尔浓度计算器

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