Frentizole 98%

Frentizole

源叶(MedMol)
S84691
26130-02-9
C15H13N3O2S
299.35
FRENTIZOLE; 1-(6-methoxybenzo[d]thiazol-2-yl)-3-phenylurea; 1-(6-methoxy-2-benzothiazolyl)-3-phenylurea; Frentizol; 1-(6-methoxy-benzothiazol-2-yl)-3-phenyl-urea;
品牌 货号 产品规格 价格(RMB) 库存(上海) 北京 武汉 南京 购买数量
源叶(MedMol) S84691-5mg 98% ¥290.00元 6 - - -
源叶(MedMol) S84691-10mg 98% ¥470.00元 7 - - -
源叶(MedMol) S84691-25mg 98% ¥770.00元 5 - - -
源叶(MedMol) S84691-50mg 98% ¥1170.00元 预计交期:2-3天 - - -
产品介绍 参考文献 质检证书(COA) 摩尔浓度计算器 相关产品

产品介绍

Frentizole, an FDA-approved immunosuppressant, is a Aβ-ABAD (binding alcohol dehydrogenase) interaction inhibitor with an IC50 value of 200 μM. Frentizole is used in studies of diseases related to rheumatoid arthritis and systemic lupus erythematosus
产品描述: Frentizole, an FDA-approved immunosuppressant, is a Aβ-ABAD (binding alcohol dehydrogenase) interaction inhibitor with an IC50 value of 200 μM. Frentizole is used in studies of diseases related to rheumatoid arthritis and systemic lupus erythematosus
靶点: Amyloid-β;BetaAmyloid
体内研究: Frentizole (8.2 or 79.9 mg/kg/day for young mice in animal feedings, 52 weeks) can extend the life span of NZB/NZW mice
参考文献: 1. Meisel AD, et al. Effect of frentizole on mitogen-induced blastogenesis in human lymphocytes. J Immunopharmacol. 1979;1(4):483-95. 2. Walker SE, et al. Prolonged lifespans in female NZB/NZW mice treated with the experimental immunoregulatory drug frentizole. Arthritis Rheum. 1982 Nov;25(11):1291-7. 3. Yuli Xie, et al. Identification of small-molecule inhibitors of the Abeta-ABAD interaction. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4657-60.
溶解性: DMSO  :  12.5  mg/mL  (41.76  mM;  Need  ultrasonic)
保存条件: -20℃
配置溶液浓度参考:
1mg 5mg 10mg
1 mM 3.341 ml 16.703 ml 33.406 ml
5 mM 0.668 ml 3.341 ml 6.681 ml
10 mM 0.334 ml 1.67 ml 3.341 ml
50 mM 0.067 ml 0.334 ml 0.668 ml
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参考文献

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