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产品描述： LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM). LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines |
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靶点：
DNA-PK:34 nM (IC50);PI3Kβ:5.8 μM (IC50);PI4Kδ:8.5 μM (IC50);DNA-PK; PI3K; PI4K |
参考文献：
1. Morrison R, et al. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur J Med Chem. 2016 Mar 3;110:326-39. |
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溶解性：
Soluble in DMSO |
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保存条件：
-20℃ |
配置溶液浓度参考：
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1mg |
5mg |
10mg |
| 1 mM |
2.413 ml |
12.063 ml |
24.127 ml |
| 5 mM |
0.483 ml |
2.413 ml |
4.825 ml |
| 10 mM |
0.241 ml |
1.206 ml |
2.413 ml |
| 50 mM |
0.048 ml |
0.241 ml |
0.483 ml |
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| 注意： |
部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。 |
上海工商
北京