• 熔点： 242-243°C

• 沸点： 556.6 °C at 760 mmHg

• 比旋光度： D -20°

• 外观： 针状晶体

• 溶解性： DMSO  :  100  mg/mL  (258.72  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 29. [IF=8] Qing Zhang et al."MMP-2 Responsive Peptide Hydrogel-Based Nanoplatform for Multimodal Tumor Therapy."International Journal of Nanomedicine.

• 28. [IF=7.9] Yi-Qing Deng et al."Compound-composed Chinese medicine of Huachansu triggers apoptosis of gastric cancer cells through increase of reactive oxygen species levels and suppression of proteasome activities."PHYTOMEDICINE.2023 Oct;:155169

• 27. [IF=4.8] Zijun Qian et al."Bufalin inhibits the proliferation of lung cancer cells by suppressing Hippo-YAP pathway."CELLULAR SIGNALLING.2023 Sep;109:110746

• 26. [IF=1.902] Ke-ke Cui et al."Quantitative analysis of multicomponents by a single marker and quality evaluation of Venenum Bufonis from different geographical origins."Biomed Chromatogr. 2019 Sep;33(9):e4555

• 25. [IF=3.565] Liqiang Qian et al."Anti-tumor Activity of Bufalin by Inhibiting c-MET Mediated MEK/ERK and PI3K/AKT Signaling Pathways in Gallbladder Cancer."J Cancer. 2020; 11(11): 3114–3123

• 24. [IF=4.379] Cao Yueting et al."The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor)."Sci Rep-Uk. 2019 Nov;9(1):1-11

• 23. [IF=4.411] Yueting Cao et al."Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins."Molecules. 2019 Jan;24(19):3595

• 22. [IF=9.381] Haiyan Hu et al."Albumin coated trimethyl chitosan-based targeting delivery platform for photothermal/chemo-synergistic cancer therapy."Carbohyd Polym. 2020 Aug;241:116335

• 21. [IF=2.193] Zhang Mei-Tuo et al."Strategic Combination of Isocratic and Gradient Elution for Simultaneous Separation of Polar Compounds in Traditional Chinese Medicines by HPLC."J Anal Methods Chem. 2018;2018:7569283

• 20. [IF=2.311] Jinlin Xie et al."Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway."Oncol Lett. 2018 Sep;16(3):3867-3873

• 19. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells."Fund Clin Pharmacol. 2017 Dec;31(6):695-700

• 18. [IF=2.748] Tao Song et al."Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L-type Ca2+ channels and contractility in rat ventricular myocytes."Fund Clin Pharmacol. 2017 Jun;31(3):340-346

• 17. [IF=3.743] Yu-Long Lan et al."Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase α1 subunit."Biomed Pharmacother. 2018 Jul;103:204

• 16. [IF=4.101] Yao Liu et al."Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice."Int J Mol Med. 2017 Aug;40(2):357-366

• 15. [IF=6.284] Lan Yu-Long et al."The sodium pump α1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway."Cell Biol Toxicol. 2019 Dec;35(6):521-539

• 14. Haiyan Hu, Qi Qi, Ziyi Dong, Xianglong Yu, Yujia Mo, Juyuan Luo, Yan Wang, Shouying Du, Yang Lu, Albumin coated trimethyl chitosan-based targeting delivery platform for photothermal/chemo-synergistic cancer therapy, Carbohydrate Polymers, Volume 241, 2020,

• 13. Xie, Jinlin, et al. "Bufalin suppresses the proliferation and metastasis of renal cell carcinoma by inhibiting the PI3K/Akt/mTOR signaling pathway." Oncology letters 16.3 (2018): 3867-3873.https://doi.org/10.3892/ol.2018.9111

• 12. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, inhibits L‐type Ca2+ channels and contractility in rat ventricular myocytes." Fundamental & clinical pharmacology 31.3 (2017): 340-346.https://doi.org/10.1111/fc

• 11. Song, Tao, et al. "Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK 293 cells." Fundamental & clinical pharmacology 31.6 (2017): 695-700.https://doi.org/10.1111/fcp.12306

• 10. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https://doi.org/10.3892/ijmm.2017.3039

• 9. Liu, Yao, et al. "Effects of bufalin on the mTOR/p70S6K pathway and apoptosis in esophageal squamous cell carcinoma in nude mice." International journal of molecular medicine 40.2 (2017): 357-366. https://doi.org/10.3892/ijmm.2017.3039

• 8. 曹月婷 崔可可 吴纪恒 等. 中华大蟾蜍毒液中蟾毒配基类成分的相关性研究[J]. 中国中药杂志 2019(9).

• 7. 房蕴歌, 王鹏飞, 朱厚达,等. 蟾酥药材和饮片(蟾酥粉)的质量标准研究[J]. 中国中药杂志, 2020(8).

• 6. 张妹砣 李玉桑 叶晓雪. 六神丸血浆药物化学的研究[J]. 绿色科技 2017 000(012):237-240.

• 5. 田志辉, 张培, 曹彦坤,等. 蟾蜍灵抑制食管癌细胞增殖、迁移和趋化运动的机制研究[J]. 中国现代医学杂志, 2015(20):50-54.

• 4. 丁妍,王小玲,邓会岩,苏丽宏,张培,刘月平.蟾蜍灵抑制Raf/MEK/细胞外信号调节激酶信号通路活化影响人食管鳞癌细胞增殖及迁移机制研究[J].中国全科医学,2015,18(21):2535-2541.

• 3. 陈砚凝, 刘尧, 王小玲,等. 蟾蜍令灵对裸鼠食管鳞癌原位移植瘤中 P70S6K 表达的影响[J]. 中国全科医学, 2015(15期):1763-1767.

• 2. 张玲玲 韩金薇 王晓琳 et al. Bufalin抑制食管癌TE13细胞迁移机制探讨[J]. 中华肿瘤防治杂志 2016 23(13):837-843.

• 1. 丁妍 王小玲 柳慧 等. Bufalin促进人食管癌细胞ECA109凋亡的研究[J]. 食管外科电子杂志 2014(02):49-54.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *