• 介绍：

   甘草查尔酮A (Licochalcone A) 是一种黄酮类化合物，具有抗癌功效，对UDP-glucuronosyltransferases (UGTs) 具有广泛抑制活性。Licochalcone A (LCA) 对 UGT1A1、1A3、1A4、1A6、1A7、1A9 和 2B7 具有强烈的抑制作用 (IC₅₀ 和K_i值均低于5 μM)。

• 熔点： 100°C

• 沸点： 532.6°Cat760mmHg

• 外观： 黄色结晶粉末

• 溶解性： DMSO  :  ≥  31  mg/mL  (91.61  mM)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 20. [IF=3.4] Han Yuxuan et al."Physicochemical parameters combined with sensory and discriminant regression, for quality and sensory characterization of licorice for both food and medicine."Journal of Food Measurement and Characterization".2024 Mar;:1-10

• 19. [IF=5.4] Xinxin Wu et al."The therapeutic efficacy and mechanism action of Si Cao formula in the treatment of psoriasis: A pilot clinical investigation and animal validation."JOURNAL OF ETHNOPHARMACOLOGY.2024 Apr;323:117662

• 18. [IF=7.2] Doudou Wang et al."Licochalcone A alleviates abnormal glucolipid metabolism and restores energy homeostasis in diet-induced diabetic mice."PHYTOTHERAPY RESEARCH.2023 Oct;:

• 17. [IF=12.7] Zhongyuan Li et al."Licochalcone A plays dual antiviral roles by inhibiting RSV and protecting against host damage."JOURNAL OF MEDICAL VIROLOGY.2023 Aug;95(8):e29059

• 16. [5.56] Liu Zidi et al."Abiotic factors and endophytes co-regulate flavone and terpenoid glycoside metabolism in Glycyrrhiza uralensis."APPLIED MICROBIOLOGY AND BIOTECHNOLOGY.2023 Mar;:1-18

• 15. [3.776] Yu-Feng Huang et al."Simultaneous determination of twenty-nine active compounds in fuzhengjiedu granules by HPLC-QQQ-MS/MS."Heliyon.2023 Feb 11;9(2):e13675

• 14. [4.927] Qinhua Zheng et al."Protective Effect of Flavonoids from Mulberry Leaf on AAPH-Induced Oxidative Damage in Sheep Erythrocytes."MOLECULES.2022 Jan;27(21):7625

• 13. [IF=5.988] Jun Li et al."Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach.."Frontiers in Pharmacology.2022 Oct;13:999950-999950

• 12. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

• 11. [IF=1.978] Chen Ming-jun et al."Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR+ ILC3."Chin J Integr Med. 2022 Apr;:1-10

• 10. [IF=6.244] Yalei Wang et al."Exploration of the Potential Mechanism of Qi Yin San Liang San Decoction in the Treatment of EGFRI-Related Adverse Skin Reactions Using Network Pharmacology and In Vitro Experiments.."Front Oncol. 2022 Mar;12:790713-790713

• 9. [IF=5.545] Yuxuan Han et al."Multi-dimensional "projection" - the impact of abiotic stresses on the content of seven active compounds and expression of related genes in Glycyrrhiza uralensis Fisch."Environ Exp Bot. 2022 May;197:104846

• 8. [IF=2.629] Li Tingting et al."Quality Assessment of Licorice Based on Quantitative Analysis of Multicomponents by Single Marker Combined with HPLC Fingerprint."Evid-Based Compl Alt. 2021;2021:8834826

• 7. [IF=4.451] Zijian Wang et al."Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat."J Funct Foods. 2019 Jun;57:190

• 6. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;:

• 5. [IF=2.896] Tian-Ming Wang et al."Simultaneous determination of 14 major components in Longhu Rendan pills by ultra-high-performance liquid chromatography coupled with electrospray ionisation tandem mass spectrometry."Anal Methods-Uk. 2014 Apr;6(9):2923-2929

• 4. Tian D-D, Wang W, Wang H-N, Sze SCW, Zhang Z-J. Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats. Molecules. 2016; 21(6):696. https://doi.org/10.3390/molecules

• 3. Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https://doi.org/10.1016/

• 2. 郭婉怡,袁蓓,汪倩,苏晓慧.甘草查尔酮A通过调控MAPK信号通路抑制MH7A细胞增殖并诱导凋亡[J].中国实验方剂学杂志,2020,26(24):68-74.

• 1. 王梨明, 范志浩, 范晓丽,等. 甘草查尔酮A对人骨肉瘤细胞增殖、凋亡的影响及其机制[J]. 广西医学, 2019, 41(012):1528-1531.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *