• 介绍：

  Aristolochic acid A (Aristolochic acid I; TR 1736) 是植物提取物 Aristolochic acids 的主要成分，其存在于 Aristolochia 和 Asarum 草本植物中。Aristolochic acid A 显着降低激活蛋白1 (AP-1) 和 NF-κB 活性。Aristolochic acid A 降低人细胞中膀胱癌相关 BLCAP 基因表达。

• 熔点： 260 °C

• 沸点： 615.5°C at 760 mmHg

• 外观： 棕色结晶

• 溶解性： 溶于乙醇、氯仿、乙醚、丙酮、醋酸、苯胺及碱，微溶于碱，几乎不溶于苯及二硫化碳。

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 12. [6.2] Ying Hu et al."Palmatine reverse aristolochic acid-induced heart failure through activating EGFR pathway via upregulating IKBKB."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Oct;285:117100

• 11. [3.6] Dian Jiao et al."A pumpless liver-on-a-chip for drug hepatotoxicity analysis."ANALYST.2024 Jul;:

• 10. [IF=7.4] Xiaoqi Chen et al."Development and Application of a Comprehensive Nontargeted Screening Strategy for Aristolochic Acid Analogues."ANALYTICAL CHEMISTRY.2024;XXXX(XXX):XXX-XXX

• 9. [3.571] Ziyan Xu et al."In vitro Nephrotoxicity and Quantitative UPLC-MS Analysis of three Aristololactams in Houttuynia Cordata."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Feb;:115289

• 8. [IF=5.168] Pan Wang et al."Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay."CHEMICO-BIOLOGICAL INTERACTIONS.2022 Nov;367:110199

• 7. [IF=6.064] Xiaohan Wang et al."Microbial degradation of aristolochic acid I by endophytic fungus A.h-Fs-1 of Asarum heterotropoides."Frontiers in Microbiology.2022; 13: 917117

• 6. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 5. [IF=4.171] Chengni Jin et al."The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy."Food Funct. 2020 Sep;11(9):7456-7467

• 4. [IF=7.46] Si-Qi Wu et al."Gold nanoclusters-based paper sensor for the visualized detection of nephrotoxic aristolochic acids."Sensor Actuat B-Chem. 2021 Aug;340:129792

• 3. [IF=7.514] Huihuang Xiong et al."Thermosensitive and magnetic molecularly imprinted polymers for selective recognition and extraction of aristolochic acid I."Food Chem. 2022 Mar;372:131250

• 2. 邵珠莹,潘金火,张月婵,蒋志涛,王雪,冯星月,王建春.6-姜酚对马兜铃酸A诱导的HK-2肾小管上皮细胞损伤的保护作用[J].中成药,2020,42(10):2744-2747.

• 1. 尹浩, 陈烁吉, 田小亭,等. 基于HPLC-Q-TOF/MS法分析马兜铃水煎剂化学成分的研究[J]. 世界科学技术:中医药现代化, 2019(7).

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *