• 介绍：

  Silibinin (Silibinin A) 为抗癌和化疗预防化合物，能抑制细胞增殖和迁移。

• 熔点： 164-174°C

• 沸点： 793°C at 760mmHg

• 比旋光度： +8 ~ +12 ° (c=0.21in acetone at 20 °C)

• 外观： 类白色结晶性粉末

• 溶解性： DMSO  :  250  mg/mL  (518.20  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 20. [IF=5] Wei Wang et al."Beneficial effects of silibinin on serum lipids, bile acids, and gut microbiota in methionine-choline-deficient diet-induced mice."Frontiers in Nutrition.2023; 10: 1257158

• 19. [IF=5.9] Xiaomei Zheng et al."Eriodictyol Alleviated LPS/D-GalN-Induced Acute Liver Injury by Inhibiting Oxidative Stress and Cell Apoptosis via PI3K/AKT Signaling Pathway."Nutrients.2023 Jan;15(20):4349

• 18. [IF=6.208] Pan Wang et al."Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2022 Jan;23(18):10747

• 17. [IF=3.246] Xu Renjie et al."Fabrication of Stable Apigenin Nanosuspension with PEG 400 as Antisolvent for Enhancing the Solubility and Bioavailability."Aaps Pharmscitech. 2022 Jan;23(1):1-11

• 16. [IF=3] Qu Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

• 15. [IF=4.268] Jie Chen et al."Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition of NF-κB and MAPK activation."Phytomedicine. 2020 Nov;78:153309

• 14. [IF=11.878] Li Xinming et al."A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage."Nat Commun. 2019 Jun;10(1):1-12

• 13. [IF=1.908] Yan Chen et al."Characterization of glutathione conjugates derived from reactive metabolites of seven silymarin isomers."Xenobiotica. 2019;49(11):1269-1278

• 12. [IF=2.977] Yan-Jiao Li et al."Silibinin exerts antidepressant effects by improving neurogenesis through BDNF/TrkB pathway."Behav Brain Res. 2018 Aug;348:184

• 11. [IF=4.5] Wang Min et al."Silibinin Prevents Autophagic Cell Death upon Oxidative Stress in Cortical Neurons and Cerebral Ischemia-Reperfusion Injury."Mol Neurobiol. 2016 Mar;53(2):932-943

• 10. Li, Fang, et al. "Lactobacillus fermentum HFY06 reduced CCl 4-induced hepatic damage in Kunming mice." RSC Advances 10.1 (2020): 1-9.https://doi.org/10.1039/C9RA08789C

• 9. Jie Chen, Dong-Li Li, Ling-Na Xie, Yu-ran Ma, Pan-Pan Wu, Chen Li, Wen-Feng Liu, Kun Zhang, Ren-Ping Zhou, Xue-Tao Xu, Xi Zheng, Xia Liu, Synergistic anti-inflammatory effects of silibinin and thymol combination on LPS-induced RAW264.7 cells by inhibition

• 8. 秦帅,吴丽丽,秦灵灵,张程斐,吴呦呦,孙伯菊,刘铜华.水飞蓟宾对C2C12细胞胰岛素抵抗的影响及机制研究[J].世界科学技术-中医药现代化,2020,22(10):3450-3455.

• 7. 张丽芳, 林霞, 冯星海,等. 超声辅助有机溶剂回流提取水飞蓟籽中水飞蓟素工艺的优化[J]. 中成药, 2019, 41(001):185-188.

• 6. 郑成凤 潘裕添 苑小宁 等. HPLC-UV-MS法对洋蓟中多酚类化合物的分析和鉴定[J]. 漳州师范学院学报(自然科学版) 2013(3):81-87.

• 5. 仲金秋, 曹玉珠, 徐宏江,等. 甘草酸二铵改善ConA致小鼠肝损伤的作用研究[J]. 天然产物研究与开发, 2018, 30(12):60-68.

• 4. 张会芳, 杨亚琛, 张久亮,等. 油菜蜂花粉加工副产物多酚对小鼠急性肝损伤的保护作用[J]. 食品安全质量检测学报, 2018, v.9(09):59-66.

• 3. 王立, 薛冰, 刘华石,等. 水飞蓟宾葡甲胺渗透泵片的制备及其释放机制考察[J]. 中国医药工业杂志, 2018.

• 2. 王立, 杨硕, 马维阳,等. 水飞蓟宾控释制剂的制备及释放机制研究[J]. 中草药, 2015(08):1145-1150.

• 1. 徐静涵, 薛芸, 王彦,等. 核壳型色谱柱-高效液相色谱法快速分离检测水飞蓟素中7种非对映异构体[J]. 化学与生物工程, 2017, 06(v.33;No.222):69-74.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *