• 介绍：

  3-Methyladenine (3-MA) 是 PI3K 的抑制剂。它通过抑制class III PI3K广泛作为自噬 (autophagy) 的抑制剂使用。

• 熔点： ~300 °C (dec.) (lit.)

• 沸点： 240.1°C at 760 mmHg

• 外观： 白色至浅黄色或浅粉色结晶粉末

• 溶解性： H2O  :  5  mg/mL  (33.52  mM;  Need  ultrasonic)
  DMSO  :  8.33  mg/mL  (55.85  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 13. [IF=6.1] Xiaoxue Fang et al."Puerarin Induces Macrophage M2 Polarization to Exert Antinonalcoholic Steatohepatitis Pharmacological Activity via the Activation of Autophagy."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY".2024;XXXX(XXX):XXX-XXX

• 12. [IF=7.9] Xiao-hua Wang et al."Shikonin suppresses rheumatoid arthritis by inducing apoptosis and autophagy via modulation of the AMPK/mTOR/ULK-1 signaling pathway."PHYTOMEDICINE".2024 Jun;128:155512

• 11. [IF=4.6] Yanghua Tang et al."An Injectable Sustained Release Hydrogel of Hyaluronic Acid Loaded with β-Ecdysterone Ameliorates Cartilage Damage in Osteoarthritis via Activating Autophagy."Advanced Therapeutics.2023 Jun;:2300101

• 10. [IF=5.4] Jianchao Si et al."Tanshinone IIA inhibited intermittent hypoxia induced neuronal injury through promoting autophagy via AMPK-mTOR signaling pathway."JOURNAL OF ETHNOPHARMACOLOGY.2023 Oct;315:116677

• 9. [IF=4.486] Cuijie Li et al."Epidermal growth factor regulation by autophagy‐mediated lncRNA H19 in murine intestinal tract after severe burn."J Cell Mol Med. 2020 May;24(10):5878-5887

• 8. [IF=5.546] Cuijie Li et al."Long noncoding RNA H19 act as a competing endogenous RNA of Let‐7g to facilitate IEC‐6 cell migration and proliferation via regulating EGF."J Cell Physiol. 2021 Apr;236(4):2881-2892

• 7. [IF=3.476] Duanyang Zhang et al."Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice."Surgery. 2017 Aug;162:408

• 6. Zhang, Duan Y. MS; Qiu, Wei MS; Jin, PeiS MD; Wang, Peng MS; Sun, Yong MD Role of autophagy and its molecular mechanisms in mice intestinal tract after severe burn, Journal of Trauma and Acute Care Surgery: October 2017 - Volume 83 - Issue 4 - p 716-724 do

• 5. Zhang, Duanyang, et al. "Autophagy can alleviate severe burn-induced damage to the intestinal tract in mice." Surgery 162.2 (2017): 408-417.https://doi.org/10.1016/j.surg.2017.04.003

• 4. 顾超,王恺纯,徐勤芬,刘微,胡道德.山柰酚调控PI3K/Akt/mTOR通路诱导人结直肠癌RKO细胞自噬[J].中南药学,2020,18(10):1668-1673.

• 3. 姜涛,凌翠敏,陈庆真,杨冰璇,林燕平,邵敏.淫羊藿苷通过提高自噬促进成骨细胞分化防治骨质疏松[J].中国组织工程研究,2021,25(17):2643-2649.

• 2. 饶春梅 成细华 任婷 孙彦波 彭霞 黄政德.加味丹参饮含药血清预处理对缺氧/复氧H9C2心肌细胞自噬相关基因Atg5和Beclin1 mRNA表达的影响[J].中国老年学杂志 2017 37(08):1821-1824.

• 1. 饶春梅 成细华 任婷 孙彦波 彭霞 黄政德.加味丹参饮含药血清对缺氧/复氧H9C2心肌细胞自噬相关蛋白LC3Ⅱ及Beclin1表达的影响[J].中医杂志 2017 58(12):1043-1048.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *