• 介绍：

   Febuxostat 是一种选择性黄嘌呤氧化酶(XO)抑制剂，Ki=0.6 nM。

• 熔点： 238-239°C

• 沸点： 536.6°C at 760 mmHg

• 外观： 结晶固体

• 溶解性： DMSO:23.7  mg/mL  (75  mM)
  Ethanol:15.8  mg/mL  (50  mM)

• 储存条件： RT

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 11. [4.8] Xiaoyan Wu et al."9-Hydroxy-8-oxypalmatine, a novel liver-mediated oxymetabolite of palmatine, alleviates hyperuricemia and kidney inflammation in hyperuricemic mice."JOURNAL OF ETHNOPHARMACOLOGY.2024 Dec;335:118606

• 10. [4.8] Shiting Gong et al."Kidney targeting and modulating macrophage polarization through AMPK signaling: Therapeutic mechanism of berberine in uric acid nephropathy."INTERNATIONAL IMMUNOPHARMACOLOGY.2024 Sep;138:112632

• 9. [4.9] Huiyan Sun et al."Targeting Liver Xor by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy."Pharmaceutics.2024 Jul;16(7):938

• 8. [6.6] Ziwei Huang et al."Supersaturated Drug Delivery System of Oxyberberine Based on Cyclodextrin Nanoaggregates: Preparation, Characterization, and in vivo Application."International Journal of Nanomedicine.

• 7. [IF=5.581] Zhi-Xu Zhang et al."Research on the Efficacy of Ganpu Vine Tea in Inhibiting Uric Acid Production."Metabolites.2023 Jun;13(6):704

• 6. [7.419] Yanlu Liu et al."Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K/Akt signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Dec;156:113941

• 5. [IF=5.195] Gaoxiang Ai et al."Hypouricemic and nephroprotective effects of palmatine from Cortex Phellodendri Amurensis: A uric acid modulator targeting Keap1-Nrf2/NLRP3 axis."JOURNAL OF ETHNOPHARMACOLOGY.2023 Jan;301:115775

• 4. [IF=6.656] Linjiang Zhong et al."Oxyberberrubine, a novel liver microsomes-mediated secondary metabolite of berberine, alleviates hyperuricemic nephropathy in mice."PHYTOMEDICINE.2023 Jan;108:154521

• 3. [IF=5.81] Xu Lieqiang et al."Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate- and Hypoxanthine-Induced Hyperuricemic Mice."Front Pharmacol. 2021 Apr;0:804

• 2. [IF=6.529] Haiyang Yang et al."Accurate quantitative determination of affinity and binding kinetics for tight binding inhibition of xanthine oxidase."Biomed Pharmacother. 2021 Jul;139:111664

• 1. Xu, Lieqiang, et al. "Anti-Hyperuricemic and Nephroprotective Effects of Dihydroberberine in Potassium Oxonate-and Hypoxanthine-Induced Hyperuricemic Mice." Frontiers in Pharmacology 12 (2021): 804.

输入产品批号：

本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *