• 介绍：

  Fluconazole (UK-49858) 是一种三唑类抗真菌剂 (antifungal)，对多种真菌具有优异的活性，尤其对Candida albicans，Fluconazole 抑制C. albicans 和 Candida kefyr 的 IC₉₉ 为 0.20 μg/mL 至 0.39 μg/mL。

• 熔点： 141℃

• 溶解性： DMSO  :  ≥  100  mg/mL  (326.51  mM)
  
  H2O  :  2  mg/mL  (6.53  mM;  Need  ultrasonic)

• 储存条件： 2-8℃

• 注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

• 18. [1.3] Wenwen Xia et al."A general and rapid LC-MS/MS method for simultaneous determination of voriconazole, posaconazole, fluconazole, itraconazole and hydroxyitraconazole in IFI patients."JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS.2024 Sep;:107565

• 17. [2.3] Li Can et al."Suppressing the virulence factors of Candida auris with baicalein through multifaceted mechanisms."ARCHIVES OF MICROBIOLOGY.2024 Aug;206(8):1-26

• 16. [14.7] Yuan Ye et al."Stable peptide-assembled nanozyme mimicking dual antifungal actions."Nature Communications.2024 Jul;15(1):1-17

• 15. [2.5] Jiahui Du et al."In vitro and in vivo inhibitory effects of the Sanghuang mushroom extracts against Candida albicans."Future Microbiology.

• 14. [IF=3.9] Yixin Liu et al."N-Butylphthalide Potentiates the Effect of Fluconazole Against Drug-Resistant Candida glabrata and Candida tropicalis. Evidence for Its Mechanism of Action."Infection and Drug Resistance.10.2147/IDR.S459378

• 13. [IF=4.7] Xiaoxiao Zhu et al."Mitochondrial Protease Oct1p Regulates Mitochondrial Homeostasis and Influences Pathogenicity through Affecting Hyphal Growth and Biofilm Formation Activities in Candida albicans."Journal of Fungi".2024 Jun;10(6):391

• 12. [IF=7.9] Kaifan Hu et al."Effect of Pulsatilla decoction on vulvovaginal candidiasis in mice. Evidences for its mechanisms of action."PHYTOMEDICINE".2024 Mar;:155515

• 11. [IF=5.988] Qun Wang et al."Study on the liver Drug’s dominant metabolic enzymes for six effective components of the Huang qi Liuyi decoction."Frontiers in Pharmacology.2023; 14: 1175896

• 10. [6.751] Xiaodi Niu et al."Antifungal activity of ginsenoside CK against Botrytis cinerea by targeting sterol 14α-demethylase cytochrome P450 (CYP51) and the application on cherry tomato preservation."POSTHARVEST BIOLOGY AND TECHNOLOGY.2023 May;199:112294

• 9. [5.195] Kaifan Hu et al."Effects of n-butanol extract of Pulsatilla decoction on the NLRP3 inflammasome in macrophages infected with Candida albicans."JOURNAL OF ETHNOPHARMACOLOGY.2022 Dec;:116041

• 8. [IF=3.571] Lin Zhou et al."Comprehensive investigation on the metabolism of emodin both in vivo and in vitro."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS.2023 Jan;223:115122

• 7. [IF=3.361] Qiang Li et al."Phosphonium-based ionic liquids as antifungal agents for conservation of heritage sandstone."Rsc Adv. 2022 Jan;12(4):1922-1931

• 6. [IF=2.211] Weifeng Hao et al."Identification of disulfiram as a potential antifungal drug by screening small molecular libraries."J Infect Chemother. 2021 May;27:696

• 5. [IF=2.211] Weifeng Hao et al."Activity of chlorhexidine acetate in combination with fluconazole against suspensions and biofilms of Candida auris."J Infect Chemother. 2022 Jan;28:29

• 4. 汪天明, 邸磊, 施高翔,等. 桑黄正丁醇提取物对白念珠菌生物膜形成的抑制作用[J]. 安徽中医药大学学报, 2019, 038(006):P.52-57.

• 3. 阎力君, 张乘蚬, 吕欣彧,等. 黄连解毒汤有效成分的提取及其对体内白色念珠菌的清除作用[J]. 中国畜牧兽医, 2019, 046(011):3414-3421.

• 2. 陈锦萍, 何海超, 蔡航,等. 海南产黄皮叶及树皮挥发油成分与抗假丝酵母菌活性的相关性研究[J]. 食品研究与开发, 2019(18).

• 1. 应泽茜,周丽娟,赵诗景,王林枭,吴亚娟,何小稳.海南产番木瓜籽挥发油的稳定性及抗假丝酵母菌活性的研究[J].时珍国医国药,2017,28(06):1323-1325.

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本计算器可帮助您计算出特定溶液中溶质的质量、溶液浓度和体积之间的关系，公式为：

质量 (mg) = 浓度 (mM) x 体积 (mL) x 分子摩尔量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *